ArticleJournal of chemical biology2014
The rising threat of fungicide resistance in plant pathogenic fungi: Botrytis as a case study.
Article in Journal of chemical biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 162 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
162 citing papers in PubMed, 1 synthesis or guideline pooled it, 507 citations in OpenAlex.
- BioprospectingFrontiers in fungal biology · 2021Pooled it
- Synthesis, SAR Analysis, and Antifungal Potency against Plant Pathogenic Fungi of New Azidopyrazoles.ACS omega · 2026Article
- FM-3224: A potent triazolinone-based fungicide with broad-spectrum activity and computational support for putative dual-target binding.Pest management science · 2026Article
- Synthesis and Antifungal Evaluation of a Ynone-Tethered 2‑Pyrone Derivative against Phytopathogenic Fungi.The plant pathology journal · 2026Article
- Hydrophobic nano-calcium superphosphate enhances leaf disease resistance via coordinated physical, biochemical, and phyllosphere responses.Journal of nanobiotechnology · 2026Article
- Effects of Temperature on Growth, Pathogenicity, and Fungicide Sensitivity of TwoJournal of fungi (Basel, Switzerland) · 2026Article
- Review
- Thymol Chemotype Thymus vulgaris L. Hydrolate: Volatile Chemical Fraction Composition and Antimicrobial Activity Against Bacterial and Fungal Pathogens.Chemistry & biodiversity · 2026Article
- Radiation Disinfection Threshold of Botrytis cinerea Under X-ray and Gamma Irradiation.The plant pathology journal · 2026Article
- The Influence of Biological Measures on Strawberry Plant Growth, Yield, and Fruit Quality.Plants (Basel, Switzerland) · 2026Article
- Low Nitrogen Concentration and Acidic pH Enhance the Antifungal Activity AgainstMicroorganisms · 2026Article
- Genomic and phenotypic characterization of AntarcticFrontiers in microbiology · 2026Article
- Timing-dependent responses ofFrontiers in plant science · 2026Article
- Synthesis, characterization, and antifungal activity of chitosan-copper nanocomposites against crop pathogens.Frontiers in fungal biology · 2026Article
- Modes of action and emerging strategies in next-generation fungicide development against phytopathogenic fungi.Frontiers in plant science · 2026Review
- Postharvest biocontrol agents in fruits and vegetables: mechanisms, applications, challenges, and future perspectives.Frontiers in nutrition · 2026Review
- Adaptation of the Phytopathogenic FungusJournal of fungi (Basel, Switzerland) · 2025Article
- Preliminary Study on the Antifungal Potential of Selected Plants as Botanical Fungicides Against Main Fungal Phytopathogens.Plants (Basel, Switzerland) · 2025Article
- Apple replant disease: unraveling the fungal enigma hidden in the rhizosphere.Stress biology · 2025Article
- Green Synthesized Copper-Oxide Nanoparticles Exhibit Antifungal Activity AgainstAntibiotics (Basel, Switzerland) · 2025Article
102 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The introduction of site-specific fungicides almost 50 years ago has revolutionized chemical plant protection, providing highly efficient, low toxicity compounds for control of fungal diseases. However, it was soon discovered that plant pathogenic fungi can adapt to fungicide treatments by mutations leading to resistance and loss of fungicide efficacy. The grey mould fungus Botrytis cinerea, a major cause of pre- and post-harvest losses in fruit and vegetable production, is notorious as a 'high risk' organism for rapid resistance development. In this review, the mechanisms and the history of fungicide resistance in Botrytis are outlined. The introduction of new fungicide classes for grey mould control was always followed by the appearance of resistance in field populations. In addition to target site resistance, B. cinerea has also developed a resistance mechanism based on drug efflux transport. Excessive spraying programmes have resulted in the selection of multiresistant strains in several countries, in particular in strawberry fields. The rapid erosion of fungicide activity against these strains represents a major challenge for the future of fungicides against Botrytis. To maintain adequate protection of intensive cultures against grey mould, strict implementation of resistance management measures are required as well as alternative strategies with non-chemical products.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.