Evidence map›Paper›PMID 25320517›Full record

ReviewWorld journal of gastroenterology2014

Potential prognostic, diagnostic and therapeutic markers for human gastric cancer.

Ming-Ming Tsai, Chia-Siu Wang, Chung-Ying Tsai, Hsiang-Cheng Chi, Yi-Hsin Tseng, Kwang-Huei Lin

Open access · hybridAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. PharmaKoVariome database for supporting genetic testing.Database : the journal of biological databases and curation · 2022
    Article
  5. Molecular and Circulating Biomarkers of Gastric Cancer.International journal of molecular sciences · 2022
    Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Methylation status of TRAF2 is associated with the diagnosis and prognosis of gastric cancer.International journal of clinical and experimental pathology · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ming-Ming TsaiMing-Ming Tsai, Department of Nursing, Chang-Gung University of Science and Technology, Taoyuan 333, Taiwan.
Chia-Siu WangMing-Ming Tsai, Department of Nursing, Chang-Gung University of Science and Technology, Taoyuan 333, Taiwan.
Chung-Ying TsaiMing-Ming Tsai, Department of Nursing, Chang-Gung University of Science and Technology, Taoyuan 333, Taiwan.
Hsiang-Cheng ChiMing-Ming Tsai, Department of Nursing, Chang-Gung University of Science and Technology, Taoyuan 333, Taiwan.
Yi-Hsin TsengMing-Ming Tsai, Department of Nursing, Chang-Gung University of Science and Technology, Taoyuan 333, Taiwan.
Kwang-Huei LinMing-Ming Tsai, Department of Nursing, Chang-Gung University of Science and Technology, Taoyuan 333, Taiwan.
Chang Gung University of Science and Technology · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The high incidence of gastric cancer (GC) and its consequent mortality rate severely threaten human health. GC is frequently not diagnosed until a relatively advanced stage. Surgery is the only potentially curative treatment. Thus, early screening and diagnosis are critical for improving prognoses in patients with GC. Gastroscopy with biopsy is an appropriate method capable of aiding the diagnosis of specific early GC tumor types; however, the stress caused by this method together with it being excessively expensive makes it difficult to use it as a routine method for screening for GC on a population basis. The currently used tumor marker assays for detecting GC are simple and rapid, but their use is limited by their low sensitivity and specificity. In recent years, several markers have been identified and tested for their clinical relevance in the management of GC. Here, we review the serum-based tumor markers for GC and their clinical significance, focusing on discoveries from microarray/proteomics research. We also review tissue-based GC tumor markers and their clinical application, focusing on discoveries from immunohistochemical research. This review provides a brief description of various tumor markers for the purposes of diagnosis, prognosis and therapeutics, and we include markers already in clinical practice and various forthcoming biomarkers.

Indexed as

Biomarkers, TumorHumansNeoplasm StagingPredictive Value of TestsReproducibility of ResultsStomach NeoplasmsBiomarkers, TumorGastric cancerPrognosisSerum-basedTissue-basedTumor marker

Identifiers

PMID25320517
PMCPMC4194563
OpenAlexW2024886520

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.