Evidence map›Paper›PMID 25320510›Full record

ArticleWorld journal of gastroenterology2014

Clinical significance of molecular diagnosis for gastric cancer lymph node micrometastasis.

Hiromichi Sonoda, Tohru Tani

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Hiromichi SonodaHiromichi Sonoda, Tohru Tani, Department of Surgery, Shiga University of Medical Science, Otsu, Shiga 520-2192, Japan.
Tohru TaniHiromichi Sonoda, Tohru Tani, Department of Surgery, Shiga University of Medical Science, Otsu, Shiga 520-2192, Japan.
Shiga University of Medical Science · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Advances in molecular diagnostic tools have allowed the identification of lymph node micrometastasis (LNM), including isolated tumor cells, in cancer patients. While immunohistochemistry and reverse transcription-polymerase chain reaction have been used to identify LNM in patients with gastric cancer, the clinical significance of this finding remains unclear. Recently, minimally invasive treatments, such as endoscopic submucosal dissection and laparoscopic surgery, are widely performed to help improve postsurgical quality of life (QOL). However, it is important to maintain the balance between QOL and curability when making treatments decision for patients with gastric cancer. If minimally invasive surgery based on accurate intraoperative LNM diagnosis was established, it could be performed safely. Therefore, we reviewed the clinical significance of LNM detected by molecular techniques as an important target for treatment decision making with gastric cancer patients.

Indexed as

Biomarkers, TumorLymph NodesMolecular Diagnostic TechniquesDecision Support TechniquesGastrectomyHumansLymphatic MetastasisLymph Node ExcisionNeoplasm MicrometastasisNeoplasm StagingPatient SelectionPredictive Value of TestsQuality of LifeStomach NeoplasmsTreatment OutcomeBiomarkers, TumorGastric cancerLymph node micrometastasisMinimally invasive surgeryMolecular techniqueSentinel lymph node

Identifiers

PMID25320510
PMCPMC4194556
OpenAlexW2063905174

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.