Evidence map›Paper›PMID 25320001›Full record

ArticleBMJ open2014

Subjective discomfort in children receiving 3 T MRI and experienced adults' perspective on children's tolerability of 7 T: a cross-sectional questionnaire survey.

I-Jun Chou, Christopher R Tench, Penny Gowland, Tim Jaspan, Rob A Dineen, Nikos Evangelou, Rasha Abdel-Fahim, William P Whitehouse, Cris S Constantinescu

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMJ open, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06257498 (Upright Open MRI for Brain Imaging in Children - a Pilot Study), which is not on this map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06257498 nacompletednot on this mapstarted 2022, after this paper: background citation

Upright Open MRI for Brain Imaging in Children - a Pilot Study

TypeinterventionalSponsorNottingham University Hospitals NHS TrustRan2022 to 2023Enrolled9ConditionsBrain TumorArmsMRI scan
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Observational
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Safety for Human MR Scanners at 7T.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2022
    Article
  13. Article
  14. Motion corrected silent ZTE neuroimaging.Magnetic resonance in medicine · 2022
    Article
  15. Article
  16. Talk to us! Communication is a key factor in improving the comfort of MRI research participants.Health expectations : an international journal of public participation in health care and health policy · 2021
    Article
  17. Silent zero TE MR neuroimaging: Current state-of-the-art and future directions.Progress in nuclear magnetic resonance spectroscopy · 2021
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

I-Jun ChouDivision of Clinical Neuroscience, School of Medicine, University of Nottingham, Nottingham, UK.
Christopher R TenchDivision of Clinical Neuroscience, School of Medicine, University of Nottingham, Nottingham, UK.
Penny GowlandSir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, UK.
Tim JaspanDepartment of Radiology, Nottingham University Hospitals Trust, Nottingham, UK.
Rob A DineenDepartment of Radiology, Nottingham University Hospitals Trust, Nottingham, UK.
Nikos EvangelouDivision of Clinical Neuroscience, School of Medicine, University of Nottingham, Nottingham, UK.
Rasha Abdel-FahimDivision of Clinical Neuroscience, School of Medicine, University of Nottingham, Nottingham, UK.
William P WhitehouseDivision of Child Health, Obstetrics and Gynaecology, School of Medicine, University of Nottingham, Nottingham, UK.
Cris S ConstantinescuDivision of Clinical Neuroscience, School of Medicine, University of Nottingham, Nottingham, UK.
University of Nottingham · GBNottingham University Hospitals NHS Trust · GBChang Gung Memorial Hospital · TW

Funding

Medical Research Council G0901321
6 · The paper itself

Abstract

objectivesTo explore the possible discomfort perceived by children participating in 7 T MRI research, and the age range in which children are most likely to tolerate it well.

designA cross-sectional survey using age-appropriate questionnaires containing six measures of subjective discomfort (general discomfort, dizziness, noisiness, claustrophobia and feeling of cold or warm).

settingFor children, 3 T clinical scanner in a tertiary referral teaching hospital; for adults, 3 and 7 T scanner in a university research building.

participantsNon-sedated children and young people under 18 years of age who underwent 3 T clinical MRI for brain or musculoskeletal scans and adult volunteers attending 7 T with or without 3 T for brain scans.

results83% (89/107) of involved individuals returned questionnaires. The most common discomfort among 31 children receiving 3 T MRI was noisiness (39%), followed by cold (19%), general discomfort (16%), dizziness (13%) and claustrophobia (10%). The noise was reported more frequently in children younger than 12 years than those older (p=0.021). The most common discomfort for 58 adults receiving 7 T MRI was noisiness (43%). In adults, there was a higher frequency of general discomfort during 7 than 3 T scans (p=0.031). More than 85% of adult respondents thought children aged 12-17 years would tolerate 7 T scans well, but only 35% and 15% thought children aged 10-11 and 8-9 years, respectively, would.

conclusionsNoisiness was the most common discomfort across all ages in 3 and 7 T scanners. Although general discomfort was more common during 7 than 3 T scans in adults, most adults thought children aged 12 years or more would tolerate 7 T MRI well. Cautious enrolment of children in 7 T MRI study is warranted, but until there is more evidence of how well those aged 12 years or more tolerate 7 T MRI, we would caution against enrolling younger children.

Indexed as

Cold TemperatureNoiseAdolescentAdultChildCross-Sectional StudiesDizzinessFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedPhobic DisordersStress, PsychologicalSurveys and QuestionnairesYoung Adult

Identifiers

PMID25320001
PMCPMC4201995
OpenAlexW1984681983

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.