ArticlePlant physiology2014
A STRESS-RESPONSIVE NAC1-regulated protein phosphatase gene rice protein phosphatase18 modulates drought and oxidative stress tolerance through abscisic acid-independent reactive oxygen species scavenging in rice.
Article in Plant physiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers, 2 of them syntheses that pooled it.
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66 citing papers in PubMed, 2 syntheses or guidelines pooled it, 164 citations in OpenAlex.
- Genome-wide association study to identify genomic loci associated with early vigor in bread wheat under simulated water deficit complemented with quantitative trait loci meta-analysis.G3 (Bethesda, Md.) · 2023Pooled it
- Gene network modules associated with abiotic stress response in tolerant rice genotypes identified by transcriptome meta-analysis.Functional & integrative genomics · 2020Pooled it
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- Assessment of Drought Tolerance Degree (DTD) method as a reliable tool for early-stage screening for drought tolerance in indica rice.BMC plant biology · 2025Article
- Oxidative Stress in Rice (Plants (Basel, Switzerland) · 2025Review
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- Integrative Analysis of Transcriptome and Metabolome Reveals the Pivotal Role of the NAM Family Genes inInternational journal of molecular sciences · 2024Article
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- Molecular Mechanisms and Regulatory Pathways Underlying Drought Stress Response in Rice.International journal of molecular sciences · 2024Review
- OsVPE2, a Member of Vacuolar Processing Enzyme Family, Decreases Chilling Tolerance of Rice.Rice (New York, N.Y.) · 2024Article
- Enhancing cold and drought tolerance in cotton: a protective role of SikCOR413PM1.BMC plant biology · 2023Article
- Starved? Time for SNAC1: A nitrogen starvation-responsive transcription factor that promotes nitrate uptake.Plant physiology · 2023Article
- Receptor-Like Cytoplasmic Kinase STK Confers Salt Tolerance in Rice.Rice (New York, N.Y.) · 2023Article
- Traces of Introgression from cAus into Tropical Japonica Observed in African Upland Rice Varieties.Rice (New York, N.Y.) · 2023Article
- Genome-Wide Identification and Abiotic Stress Response Analysis of PP2C Gene Family in Woodland and Pineapple Strawberries.International journal of molecular sciences · 2023Article
- Growth and transcriptional response of wheat and rice to the tertiary amine BMVE.Frontiers in plant science · 2023Article
- Isolation, characterization, and functional verification of salt stress response genes of NAC transcription factors inFrontiers in plant science · 2023Article
- Mutation ofInternational journal of molecular sciences · 2022Article
- Multiple forms of vitamin BStress biology · 2022Article
6 more citing papers are in PubMed but not listed here.
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6 authors at 1 institution in 1 country.
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Abstract
Plants respond to abiotic stresses through a complexity of signaling pathways, and the dephosphorylation mediated by protein phosphatase (PP) is an important event in this process. We identified a rice (Oryza sativa) PP2C gene, OsPP18, as a STRESS-RESPONSIVE NAC1 (SNAC1)-regulated downstream gene. The ospp18 mutant was more sensitive than wild-type plants to drought stress at both the seedling and panicle development stages. Rice plants with OsPP18 suppressed through artificial microRNA were also hypersensitive to drought stress. Microarray analysis of the mutant revealed that genes encoding reactive oxygen species (ROS) scavenging enzymes were down-regulated in the ospp18 mutant, and the mutant exhibited reduced activities of ROS scavenging enzymes and increased sensitivity to oxidative stresses. Overexpression of OsPP18 in rice led to enhanced osmotic and oxidative stress tolerance. The expression of OsPP18 was induced by drought stress but not induced by abscisic acid (ABA). Although OsPP18 is a typical PP2C with enzymatic activity, it did not interact with SNF1-RELATED PROTEIN KINASE2 protein kinases, which function in ABA signaling. Meanwhile, the expression of ABA-responsive genes was not affected in the ospp18 mutant, and the ABA sensitivities of the ospp18 mutant and OsPP18-overexpressing plants were also not altered. Together, these findings suggest that OsPP18 is a unique PP2C gene that is regulated by SNAC1 and confers drought and oxidative stress tolerance by regulating ROS homeostasis through ABA-independent pathways.
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