ArticleClinical journal of the American Society of Nephrology : CJASN2015
Relationship between stroke and mortality in dialysis patients.
Article in Clinical journal of the American Society of Nephrology : CJASN, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Warfarin Use and Risk of Stroke in Patients With Atrial Fibrillation Undergoing Hemodialysis: A Meta-Analysis.Medicine · 2016Pooled it
- Nationwide Trends in Stroke Among Patients Undergoing Hemodialysis by Sex and Race: An Analysis From the US Renal Database.Journal of the American Heart Association · 2025Article
- [Increased risk of bleeding in patients with atrial fibrillation and chronic kidney disease on hemodialysis treated with anticoagulants. A four center serie].Archivos de cardiologia de Mexico · 2024Article
- The Predictive Value of Atherogenic Index of Plasma, Non- High Density Lipoprotein Cholesterol (Non-HDL-C), Non-HDL-C/HDL-C, and Lipoprotein Combine Index for Stroke Incidence and Prognosis in Maintenance Hemodialysis Patients.Clinical interventions in aging · 2024Article
- Mean Platelet Volume/Platelet Count Ratio as a Predictor of Both Incidence and Prognosis of Acute Ischemic Stroke in Hemodialysis Patients.International journal of general medicine · 2023Article
- Sex Differences in Cause-specific Mortality in Japanese Dialysis Patients.Internal medicine (Tokyo, Japan) · 2022Article
- p-Cresyl Sulfate Predicts Ischemic Stroke among Patients on Hemodialysis: A Prospective Cohort Study.Disease markers · 2022Article
- Outcomes of acute ischemic stroke in kidney transplant recipients: An analysis of US Nationwide inpatient sample.Translational neuroscience · 2022Article
- Cognitive impairment in a patient with COVID-19 on hemodialysis: Too dangerous to neglect!Hemodialysis international. International Symposium on Home Hemodialysis · 2021Article
- Changes in the Risk of Stroke in Dialysis Patients: A Retrospective Analysis over the Last 40 Years.Toxins · 2021Article
- Metformin prevents stroke damage in non-diabetic female mice with chronic kidney disease.Scientific reports · 2021Article
- Same rhythm, different song-approaches to atrial fibrillation management by cardiologists and nephrologists.Clinical kidney journal · 2021Article
- Are You Tired of Working amid the Pandemic? The Role of Professional Identity and Job Satisfaction against Job Burnout.International journal of environmental research and public health · 2020Article
- Outcomes Following Ischemic Stroke in Older Patients With CKD Stages 4 and 5: A Retrospective Cohort Study.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2020Article
- Anticoagulation in Patients with End-Stage Renal Disease and Atrial Fibrillation: Confusion, Concerns and Consequences.Journal of stroke · 2020Review
- Current Trends Featuring the Bridge Between Stroke and End-Stage Renal Disease: A Review.Cureus · 2020Review
- Cellular and molecular mechanisms associated with ischemic stroke severity in female mice with chronic kidney disease.Scientific reports · 2019Article
- The Association of Atrial Fibrillation and Ischemic Stroke in Patients on Hemodialysis: A Competing Risk Analysis.Canadian journal of kidney health and disease · 2019Article
- An ensemble survival model for estimating relative residual longevity following stroke: Application to mortality data in the chronic dialysis population.Statistical methods in medical research · 2017Article
- Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
BACKGROUND AND
objectivesStroke is common in patients undergoing long-term dialysis, but the implications for mortality after stroke in these patients are not fully understood. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: A large cohort of dually-eligible (Medicare and Medicaid) patients initiating dialysis from 2000 to 2005 and surviving the first 90 days was constructed. Medicare claims were used to ascertain ischemic and hemorrhagic strokes occurring after 90-day survival. A semi-Markov model with additive hazard extension was generated to estimate the association between stroke and mortality, to calculate years of life lost after a stroke, and to determine whether race was associated with differential survival after stroke.
resultsThe cohort consisted of 69,371 individuals representing >112,000 person-years of follow-up. Mean age±SD was 60.8±15.5 years. There were 21.1 (99% confidence interval [99% CI], 20.0 to 22.3) ischemic strokes and 4.7 (99% CI, 4.2 to 5.3) hemorrhagic strokes after cohort entry per 1000 patient-years. At 30 days, mortality was 17.9% for ischemic stroke and 53.4% for hemorrhagic stroke. The adjusted hazard ratio (AHR) depended on time since entry into the cohort; for patients who experienced a stroke at 1 year after cohort entry, for example, the AHR of hemorrhagic stroke for mortality was 25.4 (99% CI, 22.4 to 28.4) at 1 week, 9.9 (99% CI, 8.4 to 11.6) at 3 months, 5.9 (99% CI, 5.0 to 7.0) at 6 months, and 1.8 (99% CI, 1.5 to 2.1) at 24 months. The corresponding AHRs for ischemic stroke were 11.7 (99% CI, 10.2 to 13.1) at 1 week, 6.6 (99% CI, 6.4 to 6.7) at 3 months, and 4.7 (99% CI, 4.5 to 4.9) at 6 months, remaining significantly >1.0 even at 48 months. Median months of life lost were 40.7 for hemorrhagic stroke and 34.6 for ischemic stroke. For both stroke types, mortality did not differ by race.
conclusionsDialysis recipients have high mortality after a stroke with corresponding decrements in remaining years of life. Poststroke mortality does not differ by race.
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Registered trials
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