Trial reportSurgical endoscopy2015
Laparoscopic versus open surgery for complicated appendicitis: a randomized controlled trial to prove safety.
Trial report in Surgical endoscopy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 4 syntheses or guidelines pooled it, 75 citations in OpenAlex.
- Laparoscopic appendicectomy is superior to open surgery for complicated appendicitis.Surgical endoscopy · 2019Pooled it
- Laparoscopic versus open surgery for suspected appendicitis.The Cochrane database of systematic reviews · 2018Pooled it
- Systematic Review and Meta-Analysis of Laparoscopic Versus Open Appendicectomy in Adults with Complicated Appendicitis: an Update of the Literature.World journal of surgery · 2017Pooled it
- Diagnosis and management of acute appendicitis. EAES consensus development conference 2015.Surgical endoscopy · 2016Guideline
- Laparoscopic versus open surgery for complicated appendicitis in adults: a randomized controlled trial.Surgical endoscopy · 2016Trial
- Laparoscopic versus open appendicectomy performed by adult general surgeons in pre-teenage years children: a single-centre experience.Annals of the Royal College of Surgeons of England · 2025Article
- Association between body composition and incisional surgical site infection after laparoscopic appendectomy for complicated appendicitis.BMC surgery · 2024Article
- Article
- Periappendiceal fluid collection on preoperative computed tomography can be an indication for interval appendectomy: a retrospective study.World journal of emergency surgery : WJES · 2022Article
- Cost-effectiveness analysis of initial nonoperative management versus emergency laparoscopic appendectomy for acute complicated appendicitis.BMC health services research · 2020Article
- The Bucharest ESTES consensus statement on peritonitis.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2020Review
- Laparoscopic versus open approach for diffuse peritonitis from appendicitis ethiology: a subgroup analysis from the Physiological parameters for Prognosis in Abdominal Sepsis (PIPAS) study.Updates in surgery · 2020Article
- Re-evaluation of purse string suture in laparoscopic appendectomy.Surgical endoscopy · 2020Article
- Exploring geographic variation in acute appendectomy in Ireland: results from a national registry study.BMJ open · 2019Article
- Efficacy of emergency laparoscopic appendectomy in treating complicated appendicitis for elderly patients.Saudi medical journal · 2017Article
- Article
- Laparoscopic versus open appendectomy in adults and children: A meta-analysis of randomized controlled trials.United European gastroenterology journal · 2017Article
- Two-port laparoscopic appendectomy with the help of a needle grasper: better cosmetic results and fewer trocars than conventional laparoscopic appendectomy.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2016Article
- Laparoscopic surgery: A qualified systematic review.World journal of methodology · 2015Article
- Acute Appendicitis in the Adult Population: Modelled Decision Analysis Supports a Conservative Approach.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo date, no randomized control trial has been performed comparing open appendectomy (OA) to laparoscopic appendectomy (LA) in complicated appendicitis. A systematic review and meta-analysis in 2010 concluded LA is advantageous to OA with less surgical site sepsis in complicated appendicitis; however, the level of evidence is weak (level 3a). The aim of the study was to determine whether LA is safe in the treatment of complicated appendicitis. Primary outcome included all-cause mortality and procedure-related mortality; secondary outcomes included intra-operative duration, rates of wound sepsis and re-intervention, length of hospital stay and re-admission rates.
methodsOne hundred and fourteen patients were randomized prospectively to either OA or LA using a computer-generated blind method. Patients who were either less than 12 years of age, had previous abdominal surgery or were pregnant were excluded. A team of senior surgeons capable of doing both OA and LA performed all procedures.
resultsThe intra-operative duration, the rate of wound sepsis, the number of re-operations, the length of hospital stay and the rate of re-admissions between the OA and LA groups did not differ statistically.
conclusionLaparoscopic appendectomy is safe in complicated appendicitis. Current Control Trials (ISRCTN92257749).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.