Evidence map›Paper›PMID 25317568›Full record

ArticleScientific reports2014

Molecular epidemiology and recombination of human enteroviruses from AFP surveillance in Yunnan, China from 2006 to 2010.

Jingjing Tang, Hiromu Yoshida, Zhengrong Ding, Zexin Tao, Jie Zhang, Bingjun Tian, Zhixian Zhao, Lifen Zhang

Abstract read
In one paragraph

Article in Scientific reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jingjing Tang1] YunnanCenter for Disease Control and Prevention, Kunming, Yunnan Province, People's Republic of China [2].
Hiromu Yoshida1] Department of Virology II, National Institute of Infectious Diseases, 4-7-1Gakuen, Musashimurayama-shi, Tokyo 208-0011, Japan [2].
Zhengrong DingYunnanCenter for Disease Control and Prevention, Kunming, Yunnan Province, People's Republic of China.
Zexin TaoShandong Provincial Key Laboratory of Infectious Disease Control and Prevention, Shandong Center for Disease Control and Prevention, Jinan, Shandong Province, People's Republic of China.
Jie ZhangYunnanCenter for Disease Control and Prevention, Kunming, Yunnan Province, People's Republic of China.
Bingjun TianYunnanCenter for Disease Control and Prevention, Kunming, Yunnan Province, People's Republic of China.
Zhixian ZhaoYunnanCenter for Disease Control and Prevention, Kunming, Yunnan Province, People's Republic of China.
Lifen ZhangYunnanCenter for Disease Control and Prevention, Kunming, Yunnan Province, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The study represents the genetic overview of non-polio enteroviruses (NPEV) isolated from acute flaccid paralysis (AFP) cases in Yunnan Province from 2006 to 2010. Molecular typing based on VP1 nucleotide sequence was carried out on 98 NPEV isolates, and 33 serotypes were identified. EV-B was detected most frequently with an overall prevalence of 71.4%, followed by EV-A (18.4%) and EV-C (10.2%). No EV-D was identified. NPEV positive rate was higher in children <3 years of age and in summer and autumn months. Clinically, 68.4% patients presented with fever, and 16 cases (16.3%) were classified as Guillain-Barré syndrome, followed by myositis (13.3%). The phylogenetic analysis on the VP1 and 3D regions of prevalent serotypes provided evidence for recombination events among them. EV-A71, an important pathogen previously demonstrated to be associated with paralysis, had also been detected (n = 8) in this study and they all belonged to genotype C4. Great genetic divergence between Yunnan isolates and strains from other regions of the world was revealed. The findings of the study are of great importance for further research on molecular evolution of EV under the circumstance of no specialized EV surveillance system in China.

Indexed as

Molecular EpidemiologyBase SequenceCapsid ProteinsChinaEnterovirusEnterovirus InfectionsGenotypeHumansParaplegiaPhylogenyRecombination, GeneticCapsid Proteins

Identifiers

PMID25317568
PMCPMC5377527

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.