Evidence map›Paper›PMID 25317367›Full record

ArticleThe primary care companion for CNS disorders2014

Underdiagnosis of attention-deficit/hyperactivity disorder in adult patients: a review of the literature.

Ylva Ginsberg, Javier Quintero, Ernie Anand, Marta Casillas, Himanshu P Upadhyaya

Open access · greenAbstract read
In one paragraph

Article in The primary care companion for CNS disorders, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 152 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
152citing papers in PubMed, 9 pooled it
9.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

152 citing papers in PubMed, 9 syntheses or guidelines pooled it, 259 citations in OpenAlex.

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  5. QbTest for Monitoring Medication Treatment Response in ADHD: A Systematic Review.Clinical practice and epidemiology in mental health : CP & EMH · 2023
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  12. Effectiveness of a Tailored Intervention for Women With Attention Deficit Hyperactivity Disorder (ADHD) and ADHD Symptoms: A Randomized Controlled Study.The American journal of occupational therapy : official publication of the American Occupational Therapy Association
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  14. Understanding antidepressant change patterns in the UK Biobank.The British journal of psychiatry : the journal of mental science · 2026
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92 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ylva GinsbergDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (Dr Ginsberg); Hospital Universitario Infanta Leonor, PSIKIDS, Madrid, Spain (Dr Quintero); Eli Lilly, Windlesham, Surrey, United Kingdom (Dr Anand); Eli Lilly, Madrid, Spain (Dr Casillas); and Eli Lilly, Indianapolis, Indiana (Dr Upadhyaya).
Javier QuinteroDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (Dr Ginsberg); Hospital Universitario Infanta Leonor, PSIKIDS, Madrid, Spain (Dr Quintero); Eli Lilly, Windlesham, Surrey, United Kingdom (Dr Anand); Eli Lilly, Madrid, Spain (Dr Casillas); and Eli Lilly, Indianapolis, Indiana (Dr Upadhyaya).
Ernie AnandDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (Dr Ginsberg); Hospital Universitario Infanta Leonor, PSIKIDS, Madrid, Spain (Dr Quintero); Eli Lilly, Windlesham, Surrey, United Kingdom (Dr Anand); Eli Lilly, Madrid, Spain (Dr Casillas); and Eli Lilly, Indianapolis, Indiana (Dr Upadhyaya).
Marta CasillasDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (Dr Ginsberg); Hospital Universitario Infanta Leonor, PSIKIDS, Madrid, Spain (Dr Quintero); Eli Lilly, Windlesham, Surrey, United Kingdom (Dr Anand); Eli Lilly, Madrid, Spain (Dr Casillas); and Eli Lilly, Indianapolis, Indiana (Dr Upadhyaya).
Himanshu P UpadhyayaDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (Dr Ginsberg); Hospital Universitario Infanta Leonor, PSIKIDS, Madrid, Spain (Dr Quintero); Eli Lilly, Windlesham, Surrey, United Kingdom (Dr Anand); Eli Lilly, Madrid, Spain (Dr Casillas); and Eli Lilly, Indianapolis, Indiana (Dr Upadhyaya).
Eli Lilly (Spain) · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo raise awareness of attention-deficit/hyperactivity disorder (ADHD) as an underdiagnosed, undertreated, often comorbid, and debilitating condition in adults. DATA SOURCES: PubMed was searched using combinations of keywords, including ADHD, adult, diagnosis, identify, prevalence, and comorbid, to find articles published between 1976 and 2013. STUDY SELECTION: In total, 99 articles were selected for inclusion on the basis of their relevance to the objective and importance to and representation of ADHD research, including international guidelines for adults with ADHD.

resultsIn a large proportion of children with ADHD, symptoms persist into adulthood. However, although adults with ADHD often experience chaotic lifestyles, with impaired educational and vocational achievement and higher risks of substance abuse and imprisonment, many remain undiagnosed and/or untreated. ADHD is usually accompanied by other psychiatric comorbidities (such as major depressive disorder, anxiety disorder, and alcohol abuse). Indeed, adults with ADHD are more likely to present to a psychiatric clinic for treatment of their comorbid disorders than for ADHD, and their ADHD symptoms are often mistaken for those of their comorbidities. Untreated ADHD in adults with psychiatric comorbidities leads to poor clinical and functional outcomes for the patient even if comorbidities are treated. Effective treatment of adults' ADHD improves symptoms, emotional lability, and patient functioning, often leading to favorable outcomes (eg, safer driving, reduced criminality). A few medications have now been approved for use in adults with ADHD, while a multimodal approach involving psychotherapy has also shown promising results. Conclusions General psychiatrists should familiarize themselves with the symptoms of ADHD in adults in order to diagnose and manage ADHD and comorbidities appropriately in these patients.

Identifiers

PMID25317367
PMCPMC4195639
OpenAlexW1996872774

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.