Evidence map›Paper›PMID 25317238›Full record

ReviewWorld journal of diabetes2014

Prognostic value of endothelial dysfunction in type 1 diabetes mellitus.

Ana Marice Ladeia, Raphael Ribeiro Sampaio, Maiara Costa Hita, Luis F Adan

Open access · hybridAbstract readReview
In one paragraph

Review in World journal of diabetes, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ana Marice LadeiaAna Marice Ladeia, Raphael Ribeiro Sampaio, Maiara Costa Hita, Bahiana School of Medicine and Public Health, Bahia Foundation for the Development of Sciences, FBDC, Salvador, Bahia 40.285-001, Brazil.
Raphael Ribeiro SampaioAna Marice Ladeia, Raphael Ribeiro Sampaio, Maiara Costa Hita, Bahiana School of Medicine and Public Health, Bahia Foundation for the Development of Sciences, FBDC, Salvador, Bahia 40.285-001, Brazil.
Maiara Costa HitaAna Marice Ladeia, Raphael Ribeiro Sampaio, Maiara Costa Hita, Bahiana School of Medicine and Public Health, Bahia Foundation for the Development of Sciences, FBDC, Salvador, Bahia 40.285-001, Brazil.
Luis F AdanAna Marice Ladeia, Raphael Ribeiro Sampaio, Maiara Costa Hita, Bahiana School of Medicine and Public Health, Bahia Foundation for the Development of Sciences, FBDC, Salvador, Bahia 40.285-001, Brazil.
Fundação Bahiana de Infectologia · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with diabetes mellitus are at high risk of developing atherosclerosis, associated with higher rates of micro and macro vascular involvement such as coronary artery disease and renal disease. The role of hyperglycemia to induce synthesis of reactive oxygen species by the oxidation of glucose, leading to an increased production of advanced glycosylation end products, as well as inflammation and oxidative stress has been proposed as a possible mechanism in the pathogenesis of endothelial dysfunction (ED). The interaction between C-peptide - the connecting segment of pro-insulin-and nitric oxide in vasodilation is also discussed. Therefore, endothelial dysfunction has been identified as an early marker of vascular disorder in type 1 and type 2 diabetes mellitus. In some other diseases, ED has been considered an independent predictor of vascular disease, regardless of the method used. Studies have demonstrated the importance of endothelial dysfunction as an useful tool for identifying the risk of vascular complications in patients with type 1 diabetes mellitus, particularly as regards to renal impairment. The aim of this review is to clarify the prognostic value of endothelial dysfunction as a marker of vascular disease in these subjects.

Indexed as

Cardiovascular diseaseEndothelial dysfunctionPathogenesisPrognosticType1 diabetes

Identifiers

PMID25317238
PMCPMC4138584
OpenAlexW1971290789

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.