Evidence map›Paper›PMID 25317127›Full record

ArticleNeural regeneration research2012

Change of retinal nerve fiber layer thickness in patients with nonarteritic inflammatory anterior ischemic optic neuropathy.

Tingting Liu, Hongsheng Bi, Xingrong Wang, Guimin Wang, Haiyan Li, Hui Wu, Yi Qu, Ying Wen, Chenyang Cong, Daoguang Wang

Abstract read
In one paragraph

Article in Neural regeneration research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tingting LiuEye Institute of Shandong Traditional Chinese Medicine University, Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine, Ophthalmology Department of Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan 250001, Shandong Province, China.
Hongsheng BiEye Institute of Shandong Traditional Chinese Medicine University, Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine, Ophthalmology Department of Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan 250001, Shandong Province, China.
Xingrong WangEye Institute of Shandong Traditional Chinese Medicine University, Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine, Ophthalmology Department of Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan 250001, Shandong Province, China.
Guimin WangEye Institute of Shandong Traditional Chinese Medicine University, Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine, Ophthalmology Department of Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan 250001, Shandong Province, China.
Haiyan LiEye Institute of Shandong Traditional Chinese Medicine University, Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine, Ophthalmology Department of Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan 250001, Shandong Province, China.
Hui WuEye Institute of Shandong Traditional Chinese Medicine University, Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine, Ophthalmology Department of Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan 250001, Shandong Province, China.
Yi QuEye Institute of Shandong Traditional Chinese Medicine University, Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine, Ophthalmology Department of Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan 250001, Shandong Province, China.
Ying WenEye Institute of Shandong Traditional Chinese Medicine University, Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine, Ophthalmology Department of Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan 250001, Shandong Province, China.
Chenyang CongEye Institute of Shandong Traditional Chinese Medicine University, Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine, Ophthalmology Department of Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan 250001, Shandong Province, China.
Daoguang WangEye Institute of Shandong Traditional Chinese Medicine University, Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine, Ophthalmology Department of Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan 250001, Shandong Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, 16 patients (19 eyes) with nonarteritic anterior ischemic optic neuropathy in the acute stage (within 4 weeks) and resolving stage (after 12 weeks) were diagnosed by a series of complete ophthalmic examinations, including fundus examination, optical coherence tomography and fluorescein fundus angiography, and visual field defects were measured with standard automated perimetry. The contralateral uninvolved eyes were used as controls. The retinal nerve fiber layer thickness was determined by optical coherence tomography which showed that the mean retinal nerve fiber layer thickness and the retinal nerve fiber layer thickness from temporal, superior, nasal and inferior quadrants were significantly higher for all measurements in the acute stage than the corresponding normal values. In comparison, the retinal nerve fiber layer thickness from each optic disc quadrant was found to be significantly lower when measured at the resolving stages, than in the control group. Statistical analysis on the correlation between optic disc nerve fiber layer thickness and visual defects demonstrated a positive correlation in the acute stage and a negative correlation in the resolving stage. Our experimental findings indicate that optical coherence tomography is a useful diagnostic method for nonarteritic anterior ischemic optic neuropathy and can be used to evaluate the effect of treatment.

Indexed as

neural regenerationnonarteritic anterior ischemic optic neuropathyoptical coherence tomographyoptic nerveperipheral nerve injuryretinal nerve fiber layervisual field

Identifiers

PMID25317127
PMCPMC4190859

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.