Evidence map›Paper›PMID 25317099›Full record

SynthesisJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2014

A systematic review of the association between obstructive sleep apnea and ventricular arrhythmias.

Akhil Raghuram, Ryan Clay, Anusha Kumbam, Larisa G Tereshchenko, Akram Khan

Open access · bronzeAbstract readSystematic Review
In one paragraph

Synthesis in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 67 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Obstructive sleep apnea and temporal changes in cardiac repolarization in patients undergoing coronary artery bypass grafting.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024
    Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
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  15. Functional outcomes of sleep predict cardiovascular intermediary outcomes and all-cause mortality in patients on incident hemodialysis.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021
    Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. The Relationship between Simple Snoring and Sleep Bruxism: A Polysomnographic Study.International journal of environmental research and public health · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Akhil RaghuramOregon Health & Science University, Portland OR.
Ryan ClayOregon Health & Science University, Portland OR.
Anusha KumbamOregon Health & Science University, Portland OR.
Larisa G TereshchenkoOregon Health & Science University, Portland OR.
Akram KhanOregon Health & Science University, Portland OR.
Oregon Health & Science University · US

Funding

Novel ECG Measures and Risk of Sudden Cardiac DeathR01HL118277 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI TERESHCHENKO, LARISA GENNADIEVNA · 2013 to 2016
$1.5M
NHLBI NIH HHS R01 HL118277
6 · The paper itself

Abstract

introductionObstructive sleep apnea (OSA) is an independent risk factor for sudden cardiac death. The aim of this review was to study the relationship between OSA and ventricular arrhythmias.

methodsPubMed, Medline, and Cochrane databases were searched with MESH headings to find studies linking OSA and ventricular arrhythmias including ventricular ectopy, ventricular tachycardia (VT), and ventricular fibrillation (VF). Studies were graded by a scoring system, and an attempt was made to pool data.

resultsThere were no matched cohort or case control studies to study the association between OSA and ventricular arrhythmias. Given data heterogeneity, pooling and meta-analysis of data were not possible. An attempt was made to judge the quality of evidence and present a systematic review. Patients with OSA were noted to have higher odds of ventricular ectopy, and were at a higher risk for ventricular arrhythmias. Associations included higher QTc dispersion and HR variability. We did not, however, find any clear evidence for a direct correlation between increased apnea hypopnea index and increased VT or VF.

conclusionsPooling and meta-analysis of studies linking OSA and ventricular arrhythmias were not possible due to heterogeneity of data. In a systemic review of studies, patients with OSA were noted to have higher odds of ventricular ectopy and arrhythmias. A single study showed that CPAP may help lower arrhythmogenicity; however, it was unclear if CPAP lowered the risk of VT. Further research should focus on studying the association of OSA and causes of sudden cardiac death, including ventricular arrhythmias.

Indexed as

Continuous Positive Airway PressureHumansRisk FactorsSleep Apnea, ObstructiveTachycardia, VentriculararrhythmiaOSAsleep apneaventricular fibrillationventricular tachycardia

Identifiers

PMID25317099
PMCPMC4173096
OpenAlexW2023000014

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.