ReviewJournal of the Turkish German Gynecological Association2014
Ovarian aging and premature ovarian failure.
Review in Journal of the Turkish German Gynecological Association, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it, 77 citations in OpenAlex.
- The impact of FMR1 gene mutations on human reproduction and development: a systematic review.Journal of assisted reproduction and genetics · 2016Pooled it
- Decreased expression of ribonucleotide reductase M2 accelerates ovarian aging by suppressing cell proliferation and inducing DNA damage in mouse theca-interstitial cells.Journal of ovarian research · 2026Article
- Critical roles of m6A demethylase FTO in ovarian aging.Biogerontology · 2026Review
- Whole-grain black rice diet rewires the single-cell transcriptomic landscape of age-related ovarian decline in mice.Science China. Life sciences · 2026Article
- Mesenchymal stem cells and platelet rich plasma in the treatment of premature ovarian insufficiency: a scoping review.Contraception and reproductive medicine · 2025Review
- De novo design of a nanoregulator for the dynamic restoration of ovarian tissue in cryopreservation and transplantation.Journal of nanobiotechnology · 2024Review
- Nicotinamide Mononucleotide and Nicotinamide Riboside Reverse Ovarian Aging in Rats Via Rebalancing Mitochondrial Fission and Fusion Mechanisms.Pharmaceutical research · 2024Article
- The Therapeutic Potential of Human Umbilical Cord Derived Mesenchymal Stem Cells for the Treatment of Premature Ovarian Failure.Stem cell reviews and reports · 2023Review
- Extracellular matrix-derived scaffolds in constructing artificial ovaries for ovarian failure: a systematic methodological review.Human reproduction open · 2023Review
- Review
- Chrysin reduces inflammation and oxidative stress and improves ovarian function in D-gal-induced premature ovarian failure.Bioengineered · 2022Article
- The role of cellular senescence in female reproductive aging and the potential for senotherapeutic interventions.Human reproduction update · 2022Review
- Impacts of endometrioma on ovarian aging from basic science to clinical management.Frontiers in endocrinology · 2022Review
- Autologous transplantation of thecal stem cells restores ovarian function in nonhuman primates.Cell discovery · 2021Article
- Protective Effects of Puerarin on Premature Ovarian Failure via Regulation of Wnt/β-catenin Signaling Pathway and Oxidative Stress.Reproductive sciences (Thousand Oaks, Calif.) · 2021Article
- Diosmin Mitigates Cyclophosphamide Induced Premature Ovarian Insufficiency in Rat Model.International journal of molecular sciences · 2021Article
- Vascular remodeling by placenta-derived mesenchymal stem cells restores ovarian function in ovariectomized rat model via the VEGF pathway.Laboratory investigation; a journal of technical methods and pathology · 2021Article
- The protective effect of fenofibrate, triptorelin, and their combination against premature ovarian failure in rats.Naunyn-Schmiedeberg's archives of pharmacology · 2021Article
- 17α-Estradiol prevents ovariectomy-mediated obesity and bone loss.Experimental gerontology · 2020Article
- Intraovarian injection of autologous human mesenchymal stem cells increases estrogen production and reduces menopausal symptoms in women with premature ovarian failure: two case reports and a review of the literature.Journal of medical case reports · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Physiological reproductive aging occurs as a result of a decrease in the number and quality of oocytes in ovarian cortex follicles. Although the reason for the decrease in the quality of the pool and follicular oocytes is not fully understood, endocrine, paracrine, genetic, and metabolic factors are thought to be effective. Nowadays, in order to understand the mechanisms of ovarian aging, genomic research has gained importance. The effect of co-factors, such as telomerase and ceramide, in the ovarian aging process is only getting ascertained with new research studies. The most important tests in the assessment of ovarian aging are antral follicle count and anti-Mullerian hormone.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.