ArticleDigestive diseases and sciences2015
Risk factors of developing interval early gastric cancer after negative endoscopy.
Article in Digestive diseases and sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed, 32 citations in OpenAlex.
- Risk factors for missed early gastric cancer: a retrospective cohort study based on pathologically confirmed cases after endoscopic submucosal dissection.Surgical endoscopy · 2026Article
- Optimizing endoscopic detection of early gastric cancer: stratification and preventive strategies for Peri-ESD diagnostic oversights.Frontiers in oncology · 2026Article
- Virtual NBI image synthesis using stable diffusion for enhanced recognition of early gastric cancer: a technical validation study.Annals of medicine · 2025Article
- Risk factors of missed early gastric cancer in endoscopic resected population: a retrospective, case-control study.Surgical endoscopy · 2024Article
- Variation in the rate of detection of minute and small early gastric cancers at diagnostic endoscopy may reflect the performance of individual endoscopists.BMJ open gastroenterology · 2023Observational
- Review
- Clinical features of gastric adenoma detected within 3 years after negative screening endoscopy in Korea.Gastroenterology report · 2023Article
- Risk stratification of patients with gastric lesions indefinite for dysplasia.The Korean journal of internal medicine · 2021Article
- Rates and Risk Factors for Interval Gastric Cancers at Screening Gastroscopy.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2021Article
- Clinical Features of False-Negative Early Gastric Cancers: A Retrospective Study of Endoscopic Submucosal Dissection Cases.Gastroenterology research and practice · 2021Article
- Common Locations of Gastric Cancer: Review of Research from the Endoscopic Submucosal Dissection Era.Journal of Korean medical science · 2019Review
- How Do We Manage Gastric Intestinal Metaplasia? A Survey of Clinical Practice Trends for Gastrointestinal Endoscopists in the United States.Digestive diseases and sciences · 2016Article
- Optimizing early upper gastrointestinal cancer detection at endoscopy.Nature reviews. Gastroenterology & hepatology · 2015Review
- Improving the Endoscopic Detection Rate in Patients with Early Gastric Cancer.Clinical endoscopy · 2015Review
- Feasibility of terahertz reflectometry for discrimination of human early gastric cancers.Biomedical optics express · 2015Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNew or missed gastric cancer rates after negative endoscopy are high. However, the clinicopathologic characteristics of missed or interval early gastric cancer (EGC) are not well known. The aim of this study was to evaluate clinicopathologic and endoscopic characteristics of missed or interval EGC after negative endoscopy.
methodsWe retrospectively analyzed 1,055 patients with EGC confirmed by endoscopic resection or surgery between June 2006 and July 2013. Referred patients with diagnosed or suspected gastric neoplasms were excluded (n = 771). Interval EGC was defined as gastric cancer diagnosed within 2 years of negative endoscopy. Clinicopathologic characteristics of patients with initially detected and interval EGC and risk factors for interval EGC were investigated.
resultsOf 284 patients, 52 had interval EGC (18.3 %; mean age 65.4 years; average interval between diagnosis and previous endoscopy, 12.6 months). Tumors were significantly smaller (1.3 vs. 1.8 cm, P < 0.001), and the incidence of metaplasia was significantly higher (90.4 vs. 65.9 %, P < 0.001) for interval EGC than for initially detected EGC. And no symptoms (50 vs. 17.7 %, P < 0.001) were significantly associated with interval EGC. However, tumor location, differentiation, gross morphology, and Helicobacter pylori infection status did not differ significantly.
conclusionsSubtle mucosal lesions with surrounding intestinal metaplasia were associated with interval EGC. Careful endoscopic screening for patients with intestinal metaplasia at short-term interval would be beneficial for decreasing interval EGC rates.
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