Evidence map›Paper›PMID 25316326›Full record

ArticleLab on a chip2014

A simple microfluidic dispenser for single-microparticle and cell samples.

A Kasukurti, C D Eggleton, S A Desai, D I Disharoon, D W M Marr

Abstract read
In one paragraph

Article in Lab on a chip, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Separation and Detection ofBiosensors · 2019
    Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

A KasukurtiChemical and Biological Engineering, Colorado School of Mines, USA. dmarr@mines.edu.
C D Eggleton
S A Desai
D I Disharoon
D W M Marr

Funding

The Plasmodial Surface Anion Channel And Malaria Parasite Nutrient AcquisitionZIAAI000882 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI DESAI, SANJAY A · 2009 to 2025
$20.5M
High-Throughput Cell Mechanical Property Testing for Label-Free AssayingR01AI079347 · NIAID · COLORADO SCHOOL OF MINES · PI EGGLETON, CHARLES DIONISIO, MARR, DAVID WM · 2009 to 2012
$1.3M
Intramural NIH HHSNIAID NIH HHS 1R01 AI079347-01NIAID NIH HHS R01 AI079347
6 · The paper itself

Abstract

Non-destructive isolation of single-cells has become an important need for many biology research laboratories; however, there is a lack of easily employed and inexpensive tools. Here, we present a single-particle sample delivery approach fabricated from simple, economical components that may address this need. In this, we employ unique flow and timing strategies to bridge the significant force and length scale differences inherent in transitioning from single particle isolation to delivery. Demonstrating this approach, we use an optical trap to isolate individual microparticles and red blood cells that are dispensed within separate 50 μl droplets off a microfluidic chip for collection into microscope slides or microtiter plates.

Indexed as

Optical TweezersCell SeparationErythrocytesHumansMicrofluidic Analytical Techniques

Identifiers

PMID25316326
PMCPMC4229394

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.