ArticleNeuroImage2015
Dynamic resting state functional connectivity in awake and anesthetized rodents.
Article in NeuroImage, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers.
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Who cites it
83 citing papers in PubMed.
- Early Multimodal Motor Training After Stroke Promotes Motor Recovery and Whole-Brain Structural Remodeling.Journal of the American Heart Association · 2026Article
- Time-resolved directional organization of brain networks: distinct strength and temporal signatures from neurophysiology to disease.bioRxiv : the preprint server for biology · 2026Article
- Predicting individual incubation of opioid craving by whole-brain functional connectivity.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Time-Varying Directed Interactions in Functional Brain Networks: Modeling and Validation.ArXiv · 2026Article
- Longitudinal resting-state fMRI of awake mice during habituation: stress, head motion, and functional connectivity.Frontiers in neuroscience · 2026Article
- Brain-wide resting-state fMRI network dynamics elicited by activation of single thalamic input.Nature communications · 2025Article
- Sex-specific signatures of GLP-1 and amylin on resting state brain activity and functional connectivity in awake rats.Neuropharmacology · 2025Article
- Parameter-dependent cell-type specific effects of transcranial focused ultrasound stimulation in an awake head-fixed rodent model.Journal of neural engineering · 2025Article
- Accurate Machine Learning-based Monitoring of Anesthesia Depth with EEG Recording.Neuroscience bulletin · 2025Article
- Sequential Deactivation Across the Hippocampus-Thalamus-mPFC Pathway During Loss of Consciousness.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Distinct Time-Resolved Brain-Wide Coactivations in Oxygenated and Deoxygenated Hemoglobin.IEEE transactions on bio-medical engineering · 2024Article
- Measuring functional connectivity in frequency-domain helps to better characterize brain function.Human brain mapping · 2024Article
- Sex differences in resting-state functional networks in awake rats.Brain structure & function · 2023Article
- Central nodes of canine functional brain networks are concentrated in the cingulate gyrus.Brain structure & function · 2023Article
- Sex differences in resting-state functional networks in awake rats.Research square · 2023Article
- Transient brain-wide coactivations and structured transitions revealed in hemodynamic imaging data.NeuroImage · 2022Article
- A Mouse Holder for Awake Functional Imaging in Unanesthetized Mice: Applications inBiosensors · 2022Article
- Light sedation with short habituation time for large-scale functional magnetic resonance imaging studies in rats.NMR in biomedicine · 2022Article
- Moving beyond the 'CAP' of the Iceberg: Intrinsic connectivity networks in fMRI are continuously engaging and overlapping.NeuroImage · 2022Article
- Functional Connectivity of the Brain Across Rodents and Humans.Frontiers in neuroscience · 2022Review
23 more citing papers are in PubMed but not listed here.
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3 authors.
Funding
Abstract
Since its introduction, resting-state functional magnetic resonance imaging (rsfMRI) has been a powerful tool for investigating functional neural networks in both normal and pathological conditions. When measuring resting-state functional connectivity (RSFC), most rsfMRI approaches do not consider its temporal variations and thus only provide the averaged RSFC over the scan time. Recently, there has been a surge of interest to investigate the dynamic characteristics of RSFC in humans, and promising results have been yielded. However, our knowledge regarding the dynamic RSFC in animals remains sparse. In the present study we utilized the single-volume co-activation method to systematically study the dynamic properties of RSFC within the networks of infralimbic cortex (IL) and primary somatosensory cortex (S1) in both awake and anesthetized rats. Our data showed that both IL and S1 networks could be decomposed into several spatially reproducible but temporally changing co-activation patterns (CAPs), suggesting that dynamic RSFC was indeed a characteristic feature in rodents. In addition, we demonstrated that anesthesia profoundly impacted the dynamic RSFC of neural circuits subserving cognitive and emotional functions but had less effects on sensorimotor systems. Finally, we examined the temporal characteristics of each CAP, and found that individual CAPs exhibited consistent temporal evolution patterns. Together, these results suggest that dynamic RSFC might be a general phenomenon in vertebrate animals. In addition, this study has paved the way for further understanding the alterations of dynamic RSFC in animal models of brain disorders.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.