ArticleInternational urogynecology journal2015
Influence of body mass index on the biomechanical properties of the human prolapsed anterior vaginal wall.
Article in International urogynecology journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 10 citations in OpenAlex.
- Influence of TVT properties on outcomes of midurethral sling procedures: high-stiffness versus low-stiffness tape.International urogynecology journal · 2016Trial
- Fiber-Reinforced Composites for Vaginal Tissue Engineering Applications.Journal of biomedical materials research. Part A · 2026Article
- Biaxial Murine Vaginal Remodeling With Reproductive Aging.Journal of biomechanical engineering · 2022Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introduction and hypothesisWe report the influence of body mass index (BMI) on the biomechanical properties of human prolapsed anterior vaginal wall (AVW) tissue samples. We hypothesize that women with AVW prolapse would have the same vaginal wall biomechanical properties regardless of their weight.
methodsFollowing Institutional Review Board approval, age-comparable postmenopausal women with symptomatic stage II-III AVW prolapse underwent excision of a short vaginal wall sample during transvaginal prolapse repair. Excised samples were subjected to uniaxial tensile testing using an Instron 5655 (Instron, Norwood, MA, USA) within 2 h of harvest to measure intrinsic biomechanical properties. Patients were divided into two groups (A: BMI <25 and B: BMI >25) to compare tissue biomechanical properties after controlling for age and parity.
resultsFrom 2011 to 2013, 28 consecutive women were studied, 13 in group A and 15 in group B. Patients with BMI >25 developed higher tissue stresses, including higher tangent moduli, at selected strain levels than patients with BMI <25.
conclusionsContrary to our hypothesis, this study observed a relationship between BMI and human AVW biomechanical properties, with more obese women having stiffer tissue properties.
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