ArticleEcotoxicology (London, England)2015
Imidacloprid induces morphological and molecular damages on testis of lizard (Podarcis sicula).
Article in Ecotoxicology (London, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 39 citations in OpenAlex.
- Neonicotinoids and the Androgen Receptor: Structural Dynamics and Potential Signaling Disruption.Biology · 2026Article
- Risk Assessment Arising from the Exposure of Terrestrial Vertebrates to Soil Contamination: Learning from Field Lizards of theJournal of xenobiotics · 2025Review
- Reproductive Effects ofToxics · 2023Article
- The Italian Wall LizardInternational journal of molecular sciences · 2022Review
- Toxic Effects on Thyroid Gland of Male Adult Lizards (International journal of molecular sciences · 2022Article
- Biological responses in pesticide exposed lizards (Podarcis siculus).Ecotoxicology (London, England) · 2021Article
- An update of the Worldwide Integrated Assessment (WIA) on systemic insecticides. Part 2: impacts on organisms and ecosystems.Environmental science and pollution research international · 2021Review
- Lizards as model organisms to evaluate environmental contamination and biomonitoring.Environmental monitoring and assessment · 2020Review
- Immunotoxicity evaluation by subchronic oral administration of clothianidin in Sprague-Dawley rats.The Journal of veterinary medical science · 2020Article
- Pesticide-induced oxidative stress and antioxidant responses in tomato (Solanum lycopersicum) seedlings.Ecotoxicology (London, England) · 2018Article
- Ecotoxicological assessment of oil-based paint using three-dimensional multi-species bio-testing model: pre- and post-bioremediation analysis.Environmental science and pollution research international · 2018Article
- Scientific Opinion on the state of the science on pesticide risk assessment for amphibians and reptiles.EFSA journal. European Food Safety Authority · 2018Article
- Prenatal and early postnatal NOAEL-dose clothianidin exposure leads to a reduction of germ cells in juvenile male mice.The Journal of veterinary medical science · 2017Article
- Effect of some commonly used pesticides on seed germination, biomass production and photosynthetic pigments in tomato (Lycopersicon esculentum).Ecotoxicology (London, England) · 2016Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The insecticide imidacloprid was evaluated under laboratory conditions in the adult male Italian wall lizards (Podarcis sicula) to assess its potential toxicity. By an acute oral test, LD50 was 503.76 mg/kg. Changes in spermatogenesis, plasma sex hormone levels and androgen and oestrogen receptor mRNAs were analysed by subchronic test and simulated environmental exposure. 15-days subchronic test, in which lizards were orally dosed on alternate days at 0, 10, 50, 100 mg/kg bw, showed a dose-dependent changes of testicular architecture and an increase of apoptotic processes. In a 30-days simulated environmental exposure spermatogenesis was arrested at secondary spermatocyte level and only few primary spermatocytes were TUNEL-positive. In all experimental groups imidacloprid was able to decrease both the level of sex hormones and the steroid receptor mRNAs. The results demonstrate that imidacloprid affects reproduction function of male lizards therefore precautions must be taken to minimize the harmful effects of this compound.
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Registered trials
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