Evidence map›Paper›PMID 25314266›Full record

ArticleJournal of abnormal psychology2014

Social cognition and functional outcome in schizophrenia: The moderating role of cardiac vagal tone.

Holly K Hamilton, Jane C Sun, Michael F Green, Kimmy S Kee, Junghee Lee, Mark Sergi, Gretchen L Sholty, Kristopher I Mathis, Christopher Jetton, Terrance J Williams and 8 more

Abstract read
In one paragraph

Article in Journal of abnormal psychology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Enhancement of aerobic fitness improves social functioning in individuals with schizophrenia.European archives of psychiatry and clinical neuroscience · 2021
    Trial
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Holly K HamiltonDepartment of Psychology.ORCID 0000-0002-4058-0949
Jane C SunDepartment of Psychology.
Michael F GreenDepartment of Psychiatry and Biobehavioral Sciences.
Kimmy S KeeDepartment of Psychology.
Junghee LeeDepartment of Psychiatry and Biobehavioral Sciences.ORCID 0000-0001-9567-8700
Mark SergiDepartment of Psychology, California State University.
Gretchen L SholtyDepartment of Psychology.
Kristopher I MathisDepartment of Psychology.
Christopher JettonDepartment of Psychology.
Terrance J WilliamsDepartment of Psychology.
Robert KernDepartment of Psychiatry and Biobehavioral Sciences.
William HoranDepartment of Psychiatry and Biobehavioral Sciences.
Alan FiskeDepartment of Anthropology.
Kenneth L SubotnikDepartment of Psychiatry and Biobehavioral Sciences.
Joseph VenturaDepartment of Psychiatry and Biobehavioral Sciences.
Gerhard HellemannDepartment of Psychiatry and Biobehavioral Sciences.
Keith H NuechterleinDepartment of Psychiatry and Biobehavioral Sciences.
Cindy M YeeDepartment of Psychology.

Funding

STRESS AND EMOTIONAL REACTIVITYP50MH066286 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI NUECHTERLEIN, KEITH H · 2003 to 2014
$18.6M
DEVELOPMENTAL PROCESSES IN SCHIZOPHRENIC DISORDERSR01MH037705 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI NUECHTERLEIN, KEITH H · 1985 to 2010
$5.1M
ATTENTIONAL AND AFFECTIVE MODULATION IN SCHIZOPHRENIAR01MH057322 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI YEE-BRADBURY, CINDY M. · 1999 to 2003
$422k
CIHR 198329NIMH NIH HHS MH37705NIMH NIH HHS MH57322NIMH NIH HHS P50 MH066286NIMH NIH HHS R01 MH037705NIMH NIH HHS R01 MH057322
6 · The paper itself

Abstract

Individuals with schizophrenia face significant challenges in daily functioning, and although social cognition predicts how well patients respond to these challenges, associated physiological mechanisms remain unspecified. The present study draws from polyvagal theory and tested the hypothesis that respiratory sinus arrhythmia (RSA), an established indicator of the capacity to self-regulate and adapt to environmental demands, combines with social cognition to predict functional outcome. Using data from 41 schizophrenia patients and 36 healthy comparison subjects, we replicated group differences in RSA and social cognition and also demonstrated that RSA and social cognition interact to predict how effectively patients manage work and independent living activities. Specifically, RSA did not enhance functional outcomes when social cognition was already strong, but higher levels of RSA enabled effective role functioning when social-cognitive performance was impaired. Jointly, RSA and social cognition accounted for 40% of the variance in outcome success, compared with 21% when evaluating social cognition alone. As polyvagal theory suggests, physiological flexibility and self-regulatory capacity may compensate for poorer social-cognitive skills among schizophrenia patients.

Indexed as

Interpersonal RelationsSocial BehaviorAdultCognitionEmotionsEmploymentFemaleHeart RateHumansInterviews as TopicMalePsychometricsRespiratory Sinus ArrhythmiaSchizophreniaSchizophrenic PsychologySocial Environment

Identifiers

PMID25314266
PMCPMC4227946

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.