ArticlePloS one2014
A new modified CKD-EPI equation for Chinese patients with type 2 diabetes.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Diagnostic value of the Modification of Diet in Renal Disease and Chronic Kidney Disease Epidemiology Collaboration equations in diabetic patients: a systematic review and meta-analysis.The Journal of international medical research · 2020Pooled it
- Comparisons of GFR estimation using the CKD Epidemiology Collaboration (CKD-EPI) equation and other creatinine-based equations in Asian population: a systematic review.International urology and nephrology · 2016Pooled it
- Subendocardial Viability Ratio Is Associated With Target Organ Damage and Hints at a Potential Independent Predictor of Cardiovascular Mortality in Older Adults: A Prospective Cohort Study.Journal of the American Heart Association · 2026Observational
- The burden of chronic kidney disease in Asia region: a review of the evidence, current challenges, and future directions.Kidney research and clinical practice · 2025Article
- Sex differences in the frailty phenotype and mortality in the I-Lan longitudinal aging study cohort.BMC geriatrics · 2024Article
- Panel estimated Glomerular Filtration Rate (GFR): Statistical considerations for maximizing accuracy in diverse clinical populations.PloS one · 2024Article
- Time to Rethink the Current Paradigm for Assessing Kidney Function in Drug Development and Beyond.Clinical pharmacology and therapeutics · 2022Review
- Association between neutrophils and renal impairment of rheumatoid arthritis: A retrospective cross-sectional study.Immunity, inflammation and disease · 2021Article
- A Novel Creatinine-Based Equation to Estimate Glomerular Filtration Rate in Chinese Population With Chronic Kidney Disease: Implications for DOACs Dosing in Atrial Fibrillation Patients.Frontiers in pharmacology · 2021Article
- Validation of the full-age spectrum equation in the approximation of glomerular filtration rate in Chinese patients with chronic kidney disease.Renal failure · 2019Article
- Asian Americans & chronic kidney disease in a nationally representative cohort.BMC nephrology · 2019Article
- A Validation Study on eGFR Equations in Chinese Patients With Diabetic or Non-diabetic CKD.Frontiers in endocrinology · 2019Article
- Methods of Estimating Kidney Function for Drug Dosing in Special Populations.Clinical pharmacokinetics · 2018Review
- Improving precision of glomerular filtration rate estimating model by ensemble learning.Journal of translational medicine · 2017Article
- SUDOSCAN, an effective tool for screening chronic kidney disease in patients with type 2 diabetes.Experimental and therapeutic medicine · 2017Article
- The modified CKD-EPI equation may be not more accurate than CKD-EPI equation in determining glomerular filtration rate in Chinese patients with chronic kidney disease.Journal of nephrology · 2017Article
- eGFRs from Asian-modified CKD-EPI and Chinese-modified CKD-EPI equations were associated better with hypertensive target organ damage in the community-dwelling elderly Chinese: the Northern Shanghai Study.Clinical interventions in aging · 2017Article
- The new Asian modified CKD-EPI equation leads to more accurate GFR estimation in Chinese patients with CKD.International urology and nephrology · 2016Article
- Development and validation of new glomerular filtration rate predicting models for Chinese patients with type 2 diabetes.Journal of translational medicine · 2015Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo improve the performance of glomerular filtration rate (GFR) estimating equation in Chinese type 2 diabetic patients by modification of the CKD-EPI equation. DESIGN AND PATIENTS: A total of 1196 subjects were enrolled. Measured GFR was calibrated to the dual plasma sample 99mTc-DTPA-GFR. GFRs estimated by the re-expressed 4-variable MDRD equation, the CKD-EPI equation and the Asian modified CKD-EPI equation were compared in 351 diabetic/non-diabetic pairs. And a new modified CKD-EPI equation was reconstructed in a total of 589 type 2 diabetic patients.
resultsIn terms of both precision and accuracy, GFR estimating equations all achieved better results in the non-diabetic cohort comparing with those in the type 2 diabetic cohort (30% accuracy, P≤0.01 for all comparisons). In the validation data set, the new modified equation showed less bias (median difference, 2.3 ml/min/1.73 m2 for the new modified equation vs. ranged from -3.8 to -7.9 ml/min/1.73 m2 for the other 3 equations [P<0.001 for all comparisons]), as was precision (IQR of the difference, 24.5 ml/min/1.73 m2 vs. ranged from 27.3 to 30.7 ml/min/1.73 m2), leading to a greater accuracy (30% accuracy, 71.4% vs. 55.2% for the re-expressed 4 variable MDRD equation and 61.0% for the Asian modified CKD-EPI equation [P = 0.001 and P = 0.02]).
conclusionA new modified CKD-EPI equation for type 2 diabetic patients was developed and validated. The new modified equation improves the performance of GFR estimation.
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