Evidence map›Paper›PMID 25313897›Full record

ArticleHealth psychology : official journal of the Division of Health Psychology, American Psychological Association2015

Dispositional optimism and perceived risk interact to predict intentions to learn genome sequencing results.

Jennifer M Taber, William M P Klein, Rebecca A Ferrer, Katie L Lewis, Leslie G Biesecker, Barbara B Biesecker

Abstract read
In one paragraph

Article in Health psychology : official journal of the Division of Health Psychology, American Psychological Association, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Trial
  2. Article
  3. Translating evidence in a priority setting partnership: knowledge gaps between healthcare providers and oesophageal cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Article
  4. Article
  5. 'I Don't Like Uncertainty, I Like to Know': How and why uveal melanoma patients consent to life expectancy prognostication.Health expectations : an international journal of public participation in health care and health policy · 2022
    Article
  6. Article
  7. Article
  8. Article
  9. Article
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  12. Associations of perceived norms with intentions to learn genomic sequencing results: Roles for attitudes and ambivalence.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2018
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Risk perceptions and health behavior.Current opinion in psychology · 2015
    Article
  18. Article
  19. Information Avoidance Tendencies, Threat Management Resources, and Interest in Genetic Sequencing Feedback.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2015
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jennifer M TaberNational Cancer Institute, National Institutes of Health.
William M P KleinNational Cancer Institute, National Institutes of Health.
Rebecca A FerrerNational Cancer Institute, National Institutes of Health.
Katie L LewisNational Human Genome Research Institute, National Institutes of Health.
Leslie G BieseckerNational Human Genome Research Institute, National Institutes of Health.
Barbara B BieseckerNational Human Genome Research Institute, National Institutes of Health.

Funding

Genomic Ascertainment - Clinical and Behavioral AspectsZIAHG200387 · NHGRI · NATIONAL HUMAN GENOME RESEARCH INSTITUTE · PI BIESECKER, LESLIE · 2013 to 2025
$15.5M
Interventions in Genetic CounselingZIAHG200317 · NHGRI · NATIONAL HUMAN GENOME RESEARCH INSTITUTE · PI BIESECKER, BARBARA BOWLES · 2009 to 2018
$7.6M
Intramural NIH HHS Z99 CA999999
6 · The paper itself

Abstract

objectiveDispositional optimism and risk perceptions are each associated with health-related behaviors and decisions and other outcomes, but little research has examined how these constructs interact, particularly in consequential health contexts. The predictive validity of risk perceptions for health-related information seeking and intentions may be improved by examining dispositional optimism as a moderator, and by testing alternate types of risk perceptions, such as comparative and experiential risk.

methodParticipants (n = 496) had their genomes sequenced as part of a National Institutes of Health pilot cohort study (ClinSeq®). Participants completed a cross-sectional baseline survey of various types of risk perceptions and intentions to learn genome sequencing results for differing disease risks (e.g., medically actionable, nonmedically actionable, carrier status) and to use this information to change their lifestyle/health behaviors.

resultsRisk perceptions (absolute, comparative, and experiential) were largely unassociated with intentions to learn sequencing results. Dispositional optimism and comparative risk perceptions interacted, however, such that individuals higher in optimism reported greater intentions to learn all 3 types of sequencing results when comparative risk was perceived to be higher than when it was perceived to be lower. This interaction was inconsistent for experiential risk and absent for absolute risk. Independent of perceived risk, participants high in dispositional optimism reported greater interest in learning risks for nonmedically actionable disease and carrier status, and greater intentions to use genome information to change their lifestyle/health behaviors.

conclusionsThe relationship between risk perceptions and intentions may depend on how risk perceptions are assessed and on degree of optimism.

Indexed as

Genetic TestingHealth BehaviorIntentionOptimismPersonalityAgedCohort StudiesCross-Sectional StudiesFemaleGenetic Predisposition to DiseaseHumansLife StyleMaleMiddle AgedUnited States

Identifiers

PMID25313897
PMCPMC4395524

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.