Evidence map›Paper›PMID 25313477›Full record

ArticleJournal of colloid and interface science2015

Facilitated preparation of bioconjugatable zwitterionic quantum dots using dual-lipid encapsulation.

Robert Shrake, Violeta G Demillo, Mojtaba Ahmadiantehrani, Xiaoshan Zhu, Nelson G Publicover, Kenneth W Hunter

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of colloid and interface science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Robert ShrakeDepartment of Electrical and Biomedical Engineering, University of Nevada, Reno, NV, USA; Biomedical Engineering Program, University of Nevada, Reno, NV, USA.
Violeta G DemilloDepartment of Electrical and Biomedical Engineering, University of Nevada, Reno, NV, USA; Biomedical Engineering Program, University of Nevada, Reno, NV, USA.
Mojtaba AhmadiantehraniDepartment of Chemical and Materials Engineering, University of Nevada, Reno, NV, USA.
Xiaoshan ZhuDepartment of Electrical and Biomedical Engineering, University of Nevada, Reno, NV, USA; Biomedical Engineering Program, University of Nevada, Reno, NV, USA. Electronic address: xzhu@unr.edu.
Nelson G PublicoverDepartment of Electrical and Biomedical Engineering, University of Nevada, Reno, NV, USA; Biomedical Engineering Program, University of Nevada, Reno, NV, USA; Department of Microbiology and Immunology, University of Nevada, Reno, NV, USA.
Kenneth W HunterBiomedical Engineering Program, University of Nevada, Reno, NV, USA; Department of Microbiology and Immunology, University of Nevada, Reno, NV, USA.
University of Nevada, Reno · US

Funding

Virtual Reality and Augmented Reality CoreP20GM103650 · NIGMS · UNIVERSITY OF NEVADA RENO · PI WEBSTER, MICHAEL A · 2012 to 2022
$20.9M
NIGMS NIH HHS 1P20GM103650-01NIGMS NIH HHS P20 GM103650
6 · The paper itself

Abstract

Zwitterionic quantum dots prepared through incorporated zwitterionic ligands on quantum dot surfaces, are being paid significant attention in biomedical applications because of their excellent colloidal stability across a wide pH and ionic strength range, antifouling surface, good biocompatibility, etc. In this work, we report a dual-lipid encapsulation approach to prepare bioconjugatable zwitterionic quantum dots using amidosulfobetaine-16 lipids, dipalmitoyl-sn-glycero-3-phosphoethanolamine lipids with functional head groups, and CuInS2/ZnS quantum dots in a tetrahydrofuran/methanol/water solvent system with sonication. Amidosulfobetaine-16 is a zwitterionic lipid and dipalmitoyl-sn-glycero-3-phosphoethanolamine, with its functional head, provides bioconjugation capability. Under sonication, tetrahydrofuran/methanol containing amidosulfobetaine-16, dipalmitoyl-sn-glycero-3-phosphoethanolamine, and hydrophobic quantum dots are dispersed in water to form droplets. Highly water-soluble tetrahydrofuran/methanol in droplets is further displaced by water, which induces the lipid self-assembling on hydrophobic surface of quantum dots and thus forms water soluble zwitterionic quantum dots. The prepared zwitterionic quantum dots maintain colloidal stability in aqueous solutions with high salinity and over a wide pH range. They are also able to be conjugated with biomolecules for bioassay with minimal nonspecific binding.

Indexed as

Biocompatible MaterialsQuantum DotsHydrogen-Ion ConcentrationLipidsMicroscopy, Electron, TransmissionOsmolar ConcentrationSpectrophotometry, UltravioletSpectroscopy, Fourier Transform InfraredBiocompatible MaterialsLipidsBioconjugationColloidal stabilityCuInS(2)/ZnSEncapsulationLipidsSurface modificationZwitterionic quantum dots

Identifiers

PMID25313477
PMCPMC4252810
OpenAlexW2013396206

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.