Evidence map›Paper›PMID 25313360›Full record

ReviewBioMed research international2014

Mucosal immunity in the female genital tract, HIV/AIDS.

Juliana Reis Machado, Marcos Vinícius da Silva, Camila Lourencini Cavellani, Marlene Antônia dos Reis, Maria Luiza Gonçalves dos Reis Monteiro, Vicente de Paula Antunes Teixeira, Rosana Rosa Miranda Corrêa

Open access · hybridAbstract readReview
In one paragraph

Review in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 80 citations in OpenAlex.

  1. Trial
  2. Review
  3. Innate Immune Protection Against HIV in the Female Genital Tract.American journal of reproductive immunology (New York, N.Y. : 1989) · 2026
    Review
  4. Article
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  7. Article
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  12. The Role of Hydrogen-Peroxide (HAntioxidants (Basel, Switzerland) · 2023
    Review
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  14. Review
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  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Juliana Reis MachadoDiscipline of General Pathology, Nephropathology Service, Federal University of Triangulo Mineiro, Rua Frei Paulino n° 30, Bairro Abadia, 38025-180 Uberaba, MG, Brazil.
Marcos Vinícius da SilvaDiscipline of Immunology, Federal University of Triangulo Mineiro, Rua Frei Paulino n° 30, Bairro Abadia, 38025-180 Uberaba, MG, Brazil.
Camila Lourencini CavellaniDiscipline of General Pathology, Nephropathology Service, Federal University of Triangulo Mineiro, Rua Frei Paulino n° 30, Bairro Abadia, 38025-180 Uberaba, MG, Brazil.
Marlene Antônia dos ReisDiscipline of General Pathology, Nephropathology Service, Federal University of Triangulo Mineiro, Rua Frei Paulino n° 30, Bairro Abadia, 38025-180 Uberaba, MG, Brazil.
Maria Luiza Gonçalves dos Reis MonteiroDiscipline of General Pathology, Nephropathology Service, Federal University of Triangulo Mineiro, Rua Frei Paulino n° 30, Bairro Abadia, 38025-180 Uberaba, MG, Brazil.
Vicente de Paula Antunes TeixeiraDiscipline of General Pathology, Nephropathology Service, Federal University of Triangulo Mineiro, Rua Frei Paulino n° 30, Bairro Abadia, 38025-180 Uberaba, MG, Brazil.
Rosana Rosa Miranda CorrêaDiscipline of General Pathology, Nephropathology Service, Federal University of Triangulo Mineiro, Rua Frei Paulino n° 30, Bairro Abadia, 38025-180 Uberaba, MG, Brazil.
Universidade Federal do Triângulo Mineiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mucosal immunity consists of innate and adaptive immune responses which can be influenced by systemic immunity. Despite having been the subject of intensive studies, it is not fully elucidated what exactly occurs after HIV contact with the female genital tract mucosa. The sexual route is the main route of HIV transmission, with an increased risk of infection in women compared to men. Several characteristics of the female genital tract make it suitable for inoculation, establishment of infection, and systemic spread of the virus, which causes local changes that may favor the development of infections by other pathogens, often called sexually transmitted diseases (STDs). The relationship of these STDs with HIV infection has been widely studied. Here we review the characteristics of mucosal immunity of the female genital tract, its alterations due to HIV/AIDS, and the characteristics of coinfections between HIV/AIDS and the most prevalent STDs.

Indexed as

Acquired Immunodeficiency SyndromeAnimalsFemaleGenitalia, FemaleHumansImmunity, MucosalLeukocytes

Identifiers

PMID25313360
PMCPMC4181941
OpenAlexW2019934331

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.