ArticleBioMed research international2014
Coating of mesh grafts for prolapse and urinary incontinence repair with autologous plasma: exploration stage of a surgical innovation.
Article in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Novel minimally invasive laser treatment of urinary incontinence in women.Lasers in surgery and medicine · 2015Trial
- Mesh-Tissue Integration of Platelet-Rich Plasma-Decellularized Amnion Scaffold-Polypropylene Mesh Sandwiches Implanted in the Vesicovaginal Spaces of Hypoestrogenic Rabbit Models: Protocol for a Randomized Controlled Trial.JMIR research protocols · 2022Article
- Outcomes collected in female pelvic floor surgical procedure registries and databases: a scoping review.International urogynecology journal · 2021Article
- The safety and efficacy of COInternational urogynecology journal · 2020Article
- Effect of the platelet-rich plasma covering of polypropylene mesh on oxidative stress, inflammation, and adhesions.International urogynecology journal · 2020Article
- Effect of Er:YAG Laser for Women with Stress Urinary Incontinence.BioMed research international · 2019Article
- Tissue reaction to urogynecologic meshes: effect of steroid soaking in two different mesh models.International urogynecology journal · 2016Article
- Can platelet-rich plasma coating improve polypropylene mesh integration? An immunohistochemical analysis in rabbits.International braz j urol : official journal of the Brazilian Society of UrologyArticle
- Effect of platelet-rich plasma on polypropylene meshes implanted in the rabbit vagina: histological analysis.International braz j urol : official journal of the Brazilian Society of UrologyArticle
- Histological response to platelet-rich plasma added to polypropylene mesh implemented in rabbits.International braz j urol : official journal of the Brazilian Society of UrologyArticle
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Authors and funding
10 authors.
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Abstract
purposeOptimized biocompatibility is a major requirement for alloplastic materials currently applied for stress urinary incontinence (SUI) and pelvic organ prolapse (POP) repair. In the preliminary studies the mesh modification by coating with autologous plasma resulted in the increased adherence score in vitro and improved biocompatibility in an animal model. The first use of plasma coated meshes in human is presented. MATERIALS AND
methodsBetween 04/2013 and 05/2014, 20 patients with the indication for SUI and POP repair were selected in a single institution. The applied meshes were modified by autologous plasma coating prior to implantation. A retrospective chart review for peri- and early postoperative complications was performed. Functional outcome and QoL were evaluated pre- and postoperatively.
resultsThe functional outcome and QoL improved significantly in all groups. Two reoperations (Grade IIIB) with the release of TVT-mesh in anesthesia due to the obstruction were needed. No other severe complications were registered.
conclusionFor the first time we applied a mesh modification in a human setting according to IDEAL criteria of surgical innovations. The procedure of mesh coating with autologous plasma is safe and a prospective randomized trial proving a positive effect of plasma coating on the biocompatibility and morbidity outcome with long-term registry is planned.
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