Evidence map›Paper›PMID 25313264›Full record

ArticleTetrahedron2014

Synthetic studies towards Zetekitoxin AB: preparation of 4,5-epi-11-hydroxy-saxitoxinol.

Aaron D Pearson, Robert M Williams

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Tetrahedron, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Natural Voltage-Gated Sodium Channel Ligands: Biosynthesis and Biology.Chembiochem : a European journal of chemical biology · 2019
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Aaron D PearsonDepartment of Chemistry, Colorado State University, Fort Collins, CO 80523, USA.
Robert M WilliamsDepartment of Chemistry, Colorado State University, Fort Collins, CO 80523, USA.
Colorado State University · US

Funding

Synthesis of Amino Acid-Containing Natural ProductsR01GM068011 · NIGMS · COLORADO STATE UNIVERSITY-FORT COLLINS · PI WILLIAMS, ROBERT MICHAEL · 2004 to 2011
$1.9M
NIGMS NIH HHS R01 GM068011
6 · The paper itself

Abstract

A concise synthesis of 4,5-epi-11-hydroxy-saxitoxinol utilizing D-ribose to direct an asymmetric Mannich reaction. This approach allows many modes of reactivity, which can be used to access various analogs of saxitoxin.

Indexed as

Diamino acidMannich reactionSaxitoxinSodium channelZetekitoxin AB

Identifiers

PMID25313264
PMCPMC4192658
OpenAlexW2007499664

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.