Evidence map›Paper›PMID 25313157›Full record

ArticleNucleic acids research2015

Xenbase, the Xenopus model organism database; new virtualized system, data types and genomes.

J Brad Karpinka, Joshua D Fortriede, Kevin A Burns, Christina James-Zorn, Virgilio G Ponferrada, Jacqueline Lee, Kamran Karimi, Aaron M Zorn, Peter D Vize

Open access · goldAbstract read
In one paragraph

Article in Nucleic acids research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed
14.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 138 citations in OpenAlex.

  1. Article
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  6. miR 31-3p Has the Highest Expression in Cesarean Scar Endometriosis.International journal of molecular sciences · 2022
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  12. Multi-tissue transcriptomes of caecilian amphibians highlight incomplete knowledge of vertebrate gene families.DNA research : an international journal for rapid publication of reports on genes and genomes · 2019
    Article
  13. Chromatin Characterization inCold Spring Harbor protocols · 2019
    Article
  14. Evolutionarily conservedProceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  15. Article
  16. Specifying neural crest cells: From chromatin to morphogens and factors in between.Wiley interdisciplinary reviews. Developmental biology · 2018
    Review
  17. Article
  18. Article
  19. Article
  20. Article

15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

J Brad KarpinkaUniversity of Calgary-Computer Science, Calgary, Alberta, Canada.
Joshua D FortriedeCincinnati Children's Research Foundation-Division of Developmental Biology, Cincinnati, OH, USA.
Kevin A BurnsCincinnati Children's Research Foundation-Division of Developmental Biology, Cincinnati, OH, USA.
Christina James-ZornCincinnati Children's Research Foundation-Division of Developmental Biology, Cincinnati, OH, USA.
Virgilio G PonferradaCincinnati Children's Research Foundation-Division of Developmental Biology, Cincinnati, OH, USA.
Jacqueline LeeUniversity of Calgary-Computer Science, Calgary, Alberta, Canada.
Kamran KarimiUniversity of Calgary-Computer Science, Calgary, Alberta, Canada.
Aaron M ZornCincinnati Children's Research Foundation-Division of Developmental Biology, Cincinnati, OH, USA.
Peter D VizeUniversity of Calgary-Computer Science, Calgary, Alberta, Canada University of Calgary-Biological Sciences, Calgary, Alberta, Canada pvize@ucalgary.ca.
Cincinnati Children's Hospital Medical Center · USUniversity of Calgary · CA

Funding

Xenbase: the Xenopus Model Organism KnowledgebaseP41HD064556 · NICHD · CINCINNATI CHILDRENS HOSP MED CTR · PI PETER D VIZE, Aaron M Zorn · 2010 to 2026
$24.9M
Xenbase: a Xenopus Model Organism DatabaseR01HD045776 · NICHD · UNIVERSITY OF CALGARY · PI VIZE, PETER D · 2005 to 2009
$1.9M
NICHD NIH HHS P41 HD064556NICHD NIH HHS P41HD064556NICHD NIH HHS R01HD045776
6 · The paper itself

Abstract

Xenbase (http://www.xenbase.org), the Xenopus frog model organism database, integrates a wide variety of data from this biomedical model genus. Two closely related species are represented: the allotetraploid Xenopus laevis that is widely used for microinjection and tissue explant-based protocols, and the diploid Xenopus tropicalis which is used for genetics and gene targeting. The two species are extremely similar and protocols, reagents and results from each species are often interchangeable. Xenbase imports, indexes, curates and manages data from both species; all of which are mapped via unique IDs and can be queried in either a species-specific or species agnostic manner. All our services have now migrated to a private cloud to achieve better performance and reliability. We have added new content, including providing full support for morpholino reagents, used to inhibit mRNA translation or splicing and binding to regulatory microRNAs. New genomes assembled by the JGI for both species and are displayed in Gbrowse and are also available for searches using BLAST. Researchers can easily navigate from genome content to gene page reports, literature, experimental reagents and many other features using hyperlinks. Xenbase has also greatly expanded image content for figures published in papers describing Xenopus research via PubMedCentral.

Indexed as

Databases, GeneticAnimalsAnimals, Genetically ModifiedDiseaseGenomeHumansInternetMicroRNAsModels, AnimalMorpholinosOligonucleotides, AntisenseXenopusXenopus laevisMicroRNAsMorpholinosOligonucleotides, Antisense

Identifiers

PMID25313157
PMCPMC4384024
OpenAlexW2165034468

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.