The relation between total joint arthroplasty and risk for serious cardiovascular events in patients with moderate-severe osteoarthritis: propensity score matched landmark analysis.

Bheeshma Ravi, Ruth Croxford, Peter C Austin, Lorraine Lipscombe, Arlene S Bierman, Paula J Harvey, Gillian A Hawker

Abstract read

In one paragraph

Article in British journal of sports medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it

0cells of the map it votes in

5citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

Effects of total knee arthroplasty on symptoms, function and activity over 5 years in knee osteoarthritis: A propensity-score matched study.Journal of experimental orthopaedics · 2025
Article
Factors lead to return to sports and recreational activity after total knee replacement - A retrospective study.SICOT-J · 2020
Article
Sports Activity Following Cementless Metaphyseal Hip Joint Arthroplasty.Journal of human kinetics · 2017
Article
Systolic and pulse pressure associate with incident knee osteoarthritis: data from the Osteoarthritis Initiative.Clinical rheumatology · 2017
Observational
Hyaluronic Acid Injections Are Associated with Delay of Total Knee Replacement Surgery in Patients with Knee Osteoarthritis: Evidence from a Large U.S. Health Claims Database.PloS one · 2015
Article

4 · The record

Corrections and comments

Reprint of
The relation between total joint arthroplasty and risk for serious cardiovascular events in patients with moderate-severe osteoarthritis: propensity score matched landmark analysis.2013

5 · Who and what money

Authors and funding

7 authors.

Bheeshma RaviDivision of Orthopaedic Surgery, Department of Surgery, University of Toronto, Canada Institute of Health Policy, Management and Evaluation, University of Toronto, Canada Women's College Research Institute, Women's College Hospital, Toronto, Canada.

Ruth CroxfordInstitute for Clinical Evaluative Sciences, Toronto, Canada.

Peter C AustinInstitute of Health Policy, Management and Evaluation, University of Toronto, Canada Institute for Clinical Evaluative Sciences, Toronto, Canada.

Lorraine LipscombeInstitute of Health Policy, Management and Evaluation, University of Toronto, Canada Women's College Research Institute, Women's College Hospital, Toronto, Canada Department of Medicine, University of Toronto, Canada.

Arlene S BiermanInstitute of Health Policy, Management and Evaluation, University of Toronto, Canada Institute for Clinical Evaluative Sciences, Toronto, Canada Department of Medicine, University of Toronto, Canada Lawrence S Bloomberg Faculty of Nursing, University of Toronto, Canada.

Paula J HarveyWomen's College Research Institute, Women's College Hospital, Toronto, Canada Department of Medicine, University of Toronto, Canada.

Gillian A HawkerInstitute of Health Policy, Management and Evaluation, University of Toronto, Canada Women's College Research Institute, Women's College Hospital, Toronto, Canada Institute for Clinical Evaluative Sciences, Toronto, Canada Department of Medicine, University of Toronto, Canada Division of Rheumatology, Department of Medicine, Women's College Hospital, Toronto, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

study questionWhat are the rates of serious cardiovascular events in those who undergo primary total joint arthroplasty (TJA) compared with those who do not within three years of initial assessment? SUMMARY ANSWER: Undergoing elective primary TJA within three years of initial assessment was associated with a significant 12.4% absolute reduction in subsequent risk of serious cardiovascular events. WHAT IS KNOWN AND WHAT THIS PAPER ADDS: Osteoarthritis is associated with increased mortality, particularly secondary to cardiovascular disease, with the risk for mortality proportional to the degree of disability secondary to the arthritis. This study suggests that management of hip or knee osteoarthritis with arthroplasty decreases the risk for subsequent serious cardiovascular events.

Identifiers

PMID25313134

DOI10.1136/bjsports-2014-f6187rep

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.