Evidence map›Paper›PMID 25313133›Full record

ArticleBritish journal of sports medicine2014

Exercise for lower limb osteoarthritis: systematic review incorporating trial sequential analysis and network meta-analysis.

Olalekan A Uthman, Danielle A van der Windt, Joanne L Jordan, Krysia S Dziedzic, Emma L Healey, George M Peat, Nadine E Foster

Abstract read
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In one paragraph

Article in British journal of sports medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 8 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Olalekan A UthmanArthritis Research UK Primary Care Centre, Keele University, Keele, Staffordshire ST5 5BG, UK Warwick Centre for Applied Health Research and Delivery (WCAHRD), Division of Health Sciences, Warwick Medical School, University of Warwick, Coventry CV4 7AL UK.
Danielle A van der WindtArthritis Research UK Primary Care Centre, Keele University, Keele, Staffordshire ST5 5BG, UK.
Joanne L JordanArthritis Research UK Primary Care Centre, Keele University, Keele, Staffordshire ST5 5BG, UK.
Krysia S DziedzicArthritis Research UK Primary Care Centre, Keele University, Keele, Staffordshire ST5 5BG, UK.
Emma L HealeyArthritis Research UK Primary Care Centre, Keele University, Keele, Staffordshire ST5 5BG, UK.
George M PeatArthritis Research UK Primary Care Centre, Keele University, Keele, Staffordshire ST5 5BG, UK.
Nadine E FosterArthritis Research UK Primary Care Centre, Keele University, Keele, Staffordshire ST5 5BG, UK.

Funding

Department of Health RP-PG-0407-10386
6 · The paper itself

Abstract

study questionWhich types of exercise intervention are most effective in relieving pain and improving function in people with lower limb osteoarthritis? SUMMARY ANSWER: As of 2002 sufficient evidence had accumulated to show significant benefit of exercise over no exercise. An approach combining exercises to increase strength, flexibility, and aerobic capacity is most likely to be effective for relieving pain and improving function. WHAT IS KNOWN AND WHAT THIS PAPER ADDS: Current international guidelines recommend therapeutic exercise (land or water based) as "core" and effective management of osteoarthritis. Evidence from this first network meta-analysis, largely based on studies in knee osteoarthritis, indicates that an intervention combining strengthening exercises with flexibility and aerobic exercise is most likely to improve outcomes of pain and function. Further trials of exercise versus no exercise are unlikely to overturn this positive result.

Identifiers

PMID25313133

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.