SynthesisOrphanet journal of rare diseases2014
Ovarian teratoma-associated anti-NMDAR encephalitis: a systematic review of reported cases.
Synthesis in Orphanet journal of rare diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
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Who cites it
40 citing papers in PubMed, 92 citations in OpenAlex.
- Anti-NMDA Receptor Encephalitis Associated with Ovarian Teratoma: A Comprehensive Review.Biomedicines · 2026Review
- Article
- Fertility outcomes and ovarian function recovery after anti-NMDAR encephalitis: A retrospective cohort study.Acta obstetricia et gynecologica Scandinavica · 2026Article
- Paraneoplastic Neurological Syndromes Associated with Ovarian Tumors: A Case Report and Systematic Review.Diagnostics (Basel, Switzerland) · 2026Article
- Article
- A Case of Ovarian Teratoma-Associated Anti-NMDA Receptor Encephalitis in the Presence of Group A Streptococcus Infection.Case reports in obstetrics and gynecology · 2026Article
- Deciphering the molecular landscape of NMDAR-E associated ovarian teratomas: a Multi-Omics approach.Journal of ovarian research · 2025Article
- Anti-N-methyl-ᴅ-aspartate receptor encephalitis in India: a case series and review of the literature.Encephalitis (Seoul, Korea) · 2025Article
- Association of ovarian teratoma with anti-N-methyl-D-aspartate receptor encephalitis: a case report and narrative review.Archives of gynecology and obstetrics · 2025Review
- Successful multi-disciplinary management of anti-NMDAR encephalitis during pregnancy.Obstetric medicine · 2025Article
- Mechanisms of autoimmune-mediated paraneoplastic syndromes: immune tolerance and disease pathogenesis.Frontiers in immunology · 2025Review
- A pediatric case of anti-GABAFrontiers in pediatrics · 2025Article
- Article
- Anti-N-Methyl-D-Aspartate (NMDA) Receptor Encephalitis Secondary to an Ovarian Dermoid Cyst.Cureus · 2024Article
- Unveiled: A Case of N-Methyl-D-Aspartate Receptor Antibody Encephalitis With Delayed Diagnosis of Ovarian Teratoma.Cureus · 2024Article
- Teratoma pathology and genomics in anti-NMDA receptor encephalitis.Annals of clinical and translational neurology · 2024Article
- Patient with concurrent anti-NMDAR autoimmune encephalitis and immature teratoma of the ovary.BMJ case reports · 2023Article
- Ovarian teratoma related anti-N-methyl-D-aspartate receptor encephalitis: A case series and review of the literature.World journal of clinical cases · 2022Article
- On the quest for hidden ovarian teratomas in therapy-refractory anti-NMDA receptor encephalitis: a case report.Neurological research and practice · 2022Article
- Ovarian resection in anti-N-methyl-D-aspartate receptor encephalitis: A comparison of surgical approaches.Frontiers in neurology · 2022Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The association of ovarian teratoma and anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a serious and potentially fatal pathology that occurs in young women and that is under-recognized. Our objectives were to analyze prevalence and outcome of this association, and increase awareness over this pathology. MEDLINE and SCOPUS for all studies published prior to November 30, 2013 including the search terms: "encephalitis" and "teratoma" were considered. All articles (119) reporting one or more cases of anti-NMDAR encephalitis and confirmed ovarian teratoma (174 cases) were included. No language restrictions were applied. Suspicious cases with no evidence of ovarian teratoma (n = 40) and another type of encephalitis also associated to ovarian teratoma (n = 20) were also considered for comparison and discussion. Data of publication and case report, surgery and outcome were collected. The distribution of published cases is heterogeneous among different countries and continents, probably in relation with level of development and health care. The mean patient age is 24 years and in the majority of cases (74%), a mature teratoma was identified, sometimes microscopically following ovarian removal or at autopsy. The clinical presentation featured psychiatric symptoms and behavioural changes, with a median delay for surgery of 28 days. Twelve women died (7%), most frequently from encephalitis-related complications. In conclusion, the association ovarian teratoma and anti-NMDAR encephalitis is relatively unknown or not reported in many countries and among gynecologists. Heightened recognition of behavioral changes, diagnosis through transvaginal ultrasound and subsequent tumor removal in addition to diagnostic confirmation through the presence of anti-NMDAR antibodies must be emphasized.
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