Evidence map›Paper›PMID 25312372›Full record

ArticleAnatomical record (Hoboken, N.J. : 2007)2014

Computational fluid dynamics as surgical planning tool: a pilot study on middle turbinate resection.

Kai Zhao, Prashant Malhotra, David Rosen, Pamela Dalton, Edmund A Pribitkin

Open access · greenAbstract readCase Reports
In one paragraph

Article in Anatomical record (Hoboken, N.J. : 2007), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.

  1. Depression and anxiety in empty nose syndrome: A systematic review and Meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Kai ZhaoMonell Chemical Senses Center, Philadelphia, Pennsylvania; Department of Otolaryngology, Thomas Jefferson University, Philadelphia, Pennsylvania.
Prashant Malhotra
David Rosen
Pamela Dalton
Edmund A Pribitkin
Thomas Jefferson University · USMonell Chemical Senses Center · US

Funding

Sensory/Medical CoreP50DC006760 · NIDCD · MONELL CHEMICAL SENSES CENTER · PI BEAUCHAMP, GARY K · 2004 to 2009
$8.6M
Nasal airflow and odorant transport: a prerequisite for normal olfactionR03DC008187 · NIDCD · MONELL CHEMICAL SENSES CENTER · PI ZHAO, KAI · 2007 to 2009
$211k
NIDCD NIH HHS 5R03DC008187NIDCD NIH HHS P50 DC00006760NIDCD NIH HHS P50 DC006760NIDCD NIH HHS R03 DC008187
6 · The paper itself

Abstract

Controversies exist regarding the resection or preservation of the middle turbinate (MT) during functional endoscopic sinus surgery. Any MT resection will perturb nasal airflow and may affect the mucociliary dynamics of the osteomeatal complex. Neither rhinometry nor computed tomography (CT) can adequately quantify nasal airflow pattern changes following surgery. This study explores the feasibility of assessing changes in nasal airflow dynamics following partial MT resection using computational fluid dynamics (CFD) techniques. We retrospectively converted the pre- and postoperative CT scans of a patient who underwent isolated partial MT concha bullosa resection into anatomically accurate three-dimensional numerical nasal models. Pre- and postsurgery nasal airflow simulations showed that the partial MT resection resulted in a shift of regional airflow towards the area of MT removal with a resultant decreased airflow velocity, decreased wall shear stress and increased local air pressure. However, the resection did not strongly affect the overall nasal airflow patterns, flow distributions in other areas of the nose, nor the odorant uptake rate to the olfactory cleft mucosa. Moreover, CFD predicted the patient's failure to perceive an improvement in his unilateral nasal obstruction following surgery. Accordingly, CFD techniques can be used to predict changes in nasal airflow dynamics following partial MT resection. However, the functional implications of this analysis await further clinical studies. Nevertheless, such techniques may potentially provide a quantitative evaluation of surgical effectiveness and may prove useful in preoperatively modeling the effects of surgical interventions.

Indexed as

HydrodynamicsPatient-Specific ModelingAgedHumansMaleNasal ObstructionParanasal SinusesPilot ProjectsTomography, X-Ray ComputedTurbinates3D modelcomputational fluid dynamicsconcha bullosafunctional endoscopic surgerynasal obstructionrhinosinusitis

Identifiers

PMID25312372
PMCPMC4435687
OpenAlexW1940927337

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.