ArticleBMC ophthalmology2014
The effect of flammer-syndrome on retinal venous pressure.
Article in BMC ophthalmology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
25 citing papers in PubMed, 44 citations in OpenAlex.
- Primary Vascular Dysregulation in Normal-Tension Glaucoma: Pathophysiology and Management.Cureus · 2026Review
- The lowering of the intraocular pressure and the retinal venous pressure by cyclophotocoagulation.BMC ophthalmology · 2026Article
- Disease Diagnosis Using Retinal Vasculature: Insights from Flammer Syndrome and AI.Brain sciences · 2025Review
- [Glaucoma Patient with Suspected Flammer Syndrome: Diagnostic Procedures and Therapeutic Implications].Klinische Monatsblatter fur Augenheilkunde · 2024Review
- Peripapillary Oxygenation and Retinal Vascular Responsiveness to Flicker Light in Primary Open Angle Glaucoma.Metabolites · 2022Article
- Modulation of Human Intraocular Pressure Using a Pneumatic System.Translational vision science & technology · 2021Article
- Treatment of Glaucoma Patients with Flammer Syndrome.Journal of clinical medicine · 2021Review
- [Vasculat treatment concepts in glaucoma patients].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2021Review
- Systemic Vascular Dysregulation May Be Associated With Lower Peripapillary Vessel Density in Non-glaucomatous Healthy Eyes: A Prospective Cross-Sectional Study.Frontiers in medicine · 2021Article
- Transient visual field impairment after cold provocation in glaucoma patients with Flammer syndrome.Restorative neurology and neuroscience · 2019Article
- In glaucoma patients, low blood pressure is accompanied by vascular dysregulation.The EPMA journal · 2018Article
- Mental stress as consequence and cause of vision loss: the dawn of psychosomatic ophthalmology for preventive and personalized medicine.The EPMA journal · 2018Review
- Residual vision activation and the brain-eye-vascular triad: Dysregulation, plasticity and restoration in low vision and blindness - a review.Restorative neurology and neuroscience · 2018Review
- Diseases potentially related to Flammer syndrome.The EPMA journal · 2017Review
- Retinal venous pressure measurements in patients with Flammer syndrome and metabolic syndrome.The EPMA journal · 2017Article
- The potential relationship between Flammer and Sjögren syndromes: the chime of dysfunction.The EPMA journal · 2017Review
- The discovery of the Flammer syndrome: a historical and personal perspective.The EPMA journal · 2017Review
- Nutritional recommendations for individuals with Flammer syndrome.The EPMA journal · 2017Review
- Breast cancer and Flammer syndrome: any symptoms in common for prediction, prevention and personalised medical approach?The EPMA journal · 2017Article
- The trilateral link between anaesthesia, perioperative visual loss and Flammer syndrome.BMC anesthesiology · 2016Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe purpose of the study was to measure the retinal venous pressure (RVP) in the eyes of primary open-angle glaucoma (POAG) patients and healthy subjects with and without a Flammer-Syndrome (FS).
methodsRVP was measured in the following four groups of patients and age- and sex-matched healthy controls: (a) 15 patients with a POAG and a FS (POAG/FS+); (b) 15 patients with a POAG but without a FS (POAG/FS-); (c) 14 healthy subjects with a FS (healthy/FS+) and (d) 16 healthy subjects without a FS (healthy/FS-). RVP was measured in all participants bilaterally by means of contact lens ophthalmodynamometry. Ophthalmodynamometry is done by applying increasing pressure on the eye via a contact lens. The minimum force required to induce a venous pulsation is called ophthalmodynamometric force (ODF). The RVP is defined and calculated as the sum of ODF and intraocular pressure (IOP) [RVP = ODF + IOP].
resultsThe participants with a FS (whether patients with POAG or healthy subjects), had a significantly higher RVP compared to subjects without a FS (p = 0.0103). Patients with a POAG and FS (POAG/FS+) had a significantly higher RVP compared to patients without a FS (POAG/FS-) (p = 0.0301). There was a notable trend for a higher RVP in the healthy/FS + group compared to the healthy/FS - group, which did not reach statistical significance (p = 0.0898).
conclusionsRVP is higher in subjects with a FS, particularly in glaucoma patients. The causal relationship needs to be further evaluated.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.