Evidence map›Paper›PMID 25312020›Full record

ReviewResearch in microbiology2015

Historical and current perspectives on Clostridium botulinum diversity.

Theresa J Smith, Karen K Hill, Brian H Raphael

Open access · greenAbstract readHistorical ArticleReview
In one paragraph

Review in Research in microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed, 2 pooled it
8.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 2 syntheses or guidelines pooled it, 160 citations in OpenAlex.

  1. Guideline
  2. Guideline
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Genomic Characterization ofChina CDC weekly · 2026
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  8. Detection of a streptogramin A O-acetyltransferase gene (Applied and environmental microbiology · 2025
    Article
  9. Article
  10. Review
  11. Opportunistic Features of Non-Pathogens (Basel, Switzerland) · 2024
    Review
  12. Review
  13. Article
  14. Review
  15. Closed genome sequence ofMicrobiology resource announcements · 2024
    Article
  16. Review
  17. Review
  18. Review
  19. Rapid SERS Detection of Botulinum Neurotoxin Type A.Nanomaterials (Basel, Switzerland) · 2023
    Article
  20. Review

10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Theresa J SmithMolecular and Translational Sciences, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD 21702, USA. Electronic address: theresa.j.smith.civ@mail.mil.
Karen K HillBioscience Division, Los Alamos National Laboratory, Los Alamos, NM 87545, USA.
Brian H RaphaelEnteric Diseases Laboratory Branch, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA.
Centers for Disease Control and Prevention · USLos Alamos National Laboratory · USUnited States Army Medical Research Institute of Infectious Diseases · US

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

For nearly one hundred years, researchers have attempted to categorize botulinum neurotoxin-producing clostridia and the toxins that they produce according to biochemical characterizations, serological comparisons, and genetic analyses. Throughout this period the bacteria and their toxins have defied such attempts at categorization. Below is a description of both historic and current Clostridium botulinum strain and neurotoxin information that illustrates how each new finding has significantly added to the knowledge of the botulinum neurotoxin-containing clostridia and their diversity.

Indexed as

Genetic VariationBacterial Typing TechniquesBotulinum ToxinsClostridium botulinumHistory, 20th CenturyHistory, 21st CenturyMolecular TypingSerotypingBotulinum ToxinsBotulinum neurotoxinsClostridium botulinumGenomicsSerotype

Identifiers

PMID25312020
PMCPMC11302483
OpenAlexW1973125376

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.