Evidence map›Paper›PMID 25311873›Full record

ArticleJournal of psychosomatic research2015

Clinical and evoked pain, personality traits, and emotional states: can familial confounding explain the associations?

Eric Strachan, Brian Poeschla, Elizabeth Dansie, Annemarie Succop, Laura Chopko, Niloofar Afari

Open access · greenAbstract readTwin Study
In one paragraph

Article in Journal of psychosomatic research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Predictors of Life Satisfaction in Native Hawaiian and Pacific Islander College Students.International journal of environmental research and public health · 2025
    Article
  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Eric Strachan *Department of Psychiatry & Behavioral Sciences, University of Washington, Seattle, WA.
Brian Poeschla *Department of Psychiatry & Behavioral Sciences, University of Washington, Seattle, WA.
Elizabeth DansieDepartment of Anesthesiology, University of Washington, Seattle, WA.
Annemarie SuccopUniversity of Washington Twin Registry, University of Washington, Seattle, WA.
Laura ChopkoDepartment of Psychiatry & Behavioral Sciences, University of Washington, Seattle, WA.
Niloofar AfariVA Center of Excellence for Stress and Mental Health, VA San Diego He althcare System, and Department of Psychiatry, University of California, San Diego, CA.
University of Washington · US

Funding

INSTITUTE FOR TRANSLATIONAL HEALTH SCIENCE (UL1): BPCAUL1RR025014 · NCRR · UNIVERSITY OF WASHINGTON · PI DISIS, MARY L. · 2007 to 2011
$51.5M
Institute of Translational Health SciencesUL1TR000423 · NCATS · UNIVERSITY OF WASHINGTON · PI DISIS, MARY L. · 2012 to 2016
$49.4M
Institute of Translational Health SciencesKL2TR000421 · NCATS · UNIVERSITY OF WASHINGTON · PI DISIS, MARY L. · 2012 to 2016
$12.6M
Institute for Translational Health Science (KL2)KL2RR025015 · NCRR · UNIVERSITY OF WASHINGTON · PI DISIS, MARY L. · 2007 to 2011
$9.3M
Institute for Translational Health Science (TL1)TL1RR025016 · NCRR · UNIVERSITY OF WASHINGTON · PI DISIS, MARY L. · 2007 to 2011
$2.7M
Institute of Translational Health SciencesTL1TR000422 · NCATS · UNIVERSITY OF WASHINGTON · PI DISIS, MARY L. · 2012 to 2016
$2.1M
Twin Study of Chronic Widespread PainR01AR051524 · NIAMS · UNIVERSITY OF WASHINGTON · PI AFARI, NILOOFAR · 2005 to 2009
$1.8M
NCATS NIH HHS KL2 TR000421NCATS NIH HHS TL1 TR000422NCATS NIH HHS UL1 TR000423NCRR NIH HHS KL2 RR025015NCRR NIH HHS KL2RR025015NCRR NIH HHS TL1 RR025016NCRR NIH HHS TL1RR025016NCRR NIH HHS UL1 RR025014NCRR NIH HHS UL1RR025014NIAMS NIH HHS R01 AR051524NIAMS NIH HHS R01AR051524
6 · The paper itself

Abstract

objectivesPain is a complex phenomenon influenced by context and person-specific factors. Affective dimensions of pain involve both enduring personality traits and fleeting emotional states. We examined how personality traits and emotional states are linked with clinical and evoked pain in a twin sample.

methods99 female twin pairs were evaluated for clinical and evoked pain using the McGill Pain Questionnaire (MPQ) and dolorimetry, and completed the 120-item International Personality Item Pool (IPIP), the Positive and Negative Affect Scale (PANAS), and ratings of stress and mood. Using a co-twin control design we examined a) the relationship of personality traits and emotional states with clinical and evoked pain and b) whether genetics and common environment (i.e. familial factors) may account for the associations.

resultsNeuroticism was associated with the sensory component of the MPQ; this relationship was not confounded by familial factors. None of the emotional state measures was associated with the MPQ. PANAS negative affect was associated with lower evoked pressure pain threshold and tolerance; these associations were confounded by familial factors. There were no associations between IPIP traits and evoked pain.

conclusionsA relationship exists between neuroticism and clinical pain that is not confounded by familial factors. There is no similar relationship between negative emotional states and clinical pain. In contrast, the relationship between negative emotional states and evoked pain is strong while the relationship with enduring personality traits is weak. The relationship between negative emotional states and evoked pain appears to be non-causal and due to familial factors.

Indexed as

AffectEmotionsPersonalityAdultAnxiety DisordersFemaleHumansMental HealthNeuroticismPainPain MeasurementPersonality InventoryStress, PsychologicalTwinsClinical painEmotionsEvoked painExtraversionNeuroticismPersonalityTwins

Identifiers

PMID25311873
PMCPMC4272603
OpenAlexW2077283604

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.