ArticleBMC plant biology2014
MYB80 homologues in Arabidopsis, cotton and Brassica: regulation and functional conservation in tapetal and pollen development.
Article in BMC plant biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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29 citing papers in PubMed, 72 citations in OpenAlex.
- Key genes and molecular mechanisms responsible for male sterility revealed by transcriptome analysis in cotton.Plant cell reports · 2025Article
- Single-Cell Transcriptome Atlas and Dynamic Regulatory Mechanisms of Anther Development in Alfalfa (Medicago sativa L.).Plant biotechnology journal · 2025Article
- Exploring candidate genes related to pollen abortion in garlic (Allium sativum) based on cytological studies and transcriptome sequencing.Journal of plant research · 2025Article
- Genome-wide identification of the Medicago sativa L. MYB family and its transcriptional dynamics during pollen development.BMC plant biology · 2025Article
- Unlocking male sterility in horticultural crops through gene editing technology for precision breeding applications: presentation of a case study in tomato.Frontiers in plant science · 2025Article
- The MYB family and their response to abiotic stress in ginger (Zingiber officinale Roscoe).BMC genomics · 2024Article
- Regulation of developmental gatekeeping and cell fate transition by the calpain protease DEK1 in Physcomitrium patens.Communications biology · 2024Article
- Genome-wide identification and characterization of NAC transcription factor family members in Trifolium pratense and expression analysis under lead stress.BMC genomics · 2024Article
- The transcription factors and pathways underpinning male reproductive development in Arabidopsis.Frontiers in plant science · 2024Review
- Biosynthesis and transport of pollen coat precursors in angiosperms.Nature plants · 2023Review
- Downregulation ofFrontiers in plant science · 2023Article
- MYB2 Is Important for Tapetal PCD and Pollen Development by Directly Activating Protease Expression inInternational journal of molecular sciences · 2022Article
- Morphological analysis and stage determination of anther development in Sorghum [Sorghum bicolor (L.) Moench].Planta · 2022Article
- The SlHB8 acts as a negative regulator in tapetum development and pollen wall formation in Tomato.Horticulture research · 2022Article
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- Differential responses of anthers of stress tolerant and sensitive wheat cultivars to high temperature stress.Planta · 2021Article
- The MYB transcription factor Baymax1 plays a critical role in rice male fertility.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2021Article
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- Article
- OsMYB80 Regulates Anther Development and Pollen Fertility by Targeting Multiple Biological Pathways.Plant & cell physiology · 2020Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe Arabidopsis AtMYB80 transcription factor regulates genes involved in pollen development and controls the timing of tapetal programmed cell death (PCD). Downregulation of AtMYB80 expression precedes tapetal degradation. Inhibition of AtMYB80 expression results in complete male sterility. Full-length AtMYB80 homologs have been isolated in wheat, rice, barley and canola (C genome).
resultsThe complete sequences of MYB80 genes from the Brassica. napus (A gene), B. juncea (A gene), B. oleracea (C gene) and the two orthologs from cotton (Gossypium hirsutum) were determined. The deduced amino acid sequences possess a highly conserved MYB domain, 44-amino acid region and 18-amino acid C-terminal sequence. The cotton MYB80 protein can fully restore fertility of the atmyb80 mutant, while removal of the 44 amino acid sequence abolishes its function. Two conserved MYB cis-elements in the AtMYB80 promoter are required for downregulation of MYB80 expression in anthers, apparently via negative auto-regulation. In cotton, tapetal degradation occurs at a slightly earlier stage of anther development than in Arabidopsis, consistent with an earlier increase and subsequent downregulation in GhMYB80 expression. The MYB80 homologs fused with the EAR repressor motif have been shown to induce male sterility in Arabidopsis. Constructs were designed to maximize the level of male sterility.
conclusionsMYB80 genes are conserved in structure and function in all monocot and dicot species so far examined. Expression patterns of MYB80 in these species are also highly similar. The reversible male sterility system developed in Arabidopsis by manipulating MYB80 expression should be applicable to all major crops.
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