ArticleJournal of Parkinson's disease2015
Side and type of initial motor symptom influences visuospatial functioning in Parkinson's disease.
Article in Journal of Parkinson's disease, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Differences in Spatial Cognition and Motor-Cognitive Integration by Side of Onset in People with Parkinson's Disease.Brain sciences · 2026Article
- Novel psychophysical line bisection task using brief stimulus presentation reveals no horizontal bias in left-onset parkinson's disease.Scientific reports · 2026Article
- Visual Dysfunction in Parkinson's Disease.Brain sciences · 2023Review
- Gray and white matter alterations in different predominant side and type of motor symptom in Parkinson's disease.CNS neuroscience & therapeutics · 2022Article
- Subthalamic deep brain stimulation affects heading perception in Parkinson's disease.Journal of neurology · 2022Article
- Taking the Time to Assess Cognition in Parkinson's Disease: The Clock Drawing Test.Journal of Parkinson's disease · 2022Article
- Severity-Dependent Effects of Parkinson's Disease on Perception of Visual and Vestibular Heading.Movement disorders : official journal of the Movement Disorder Society · 2021Article
- Dopaminergic Basis of Spatial Deficits in Early Parkinson's Disease.Cerebral cortex communications · 2021Article
- Spatial judgment in Parkinson's disease: Contributions of attentional and executive dysfunction.Behavioral neuroscience · 2019Article
- The Body Position Spatial Task, a Test of Whole-Body Spatial Cognition: Comparison Between Adults With and Without Parkinson Disease.Neurorehabilitation and neural repair · 2018Article
- Cognitive and behavioral disorders in Parkinson's disease: an update. I: cognitive impairments.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2018Review
- Age and Graphomotor Decision Making Assessed with the Digital Clock Drawing Test: The Framingham Heart Study.Journal of Alzheimer's disease : JAD · 2017Article
- Does Side of Onset Influence the Pattern of Cerebral Atrophy in Parkinson's Disease?Frontiers in neurology · 2016Article
- Normal discrimination of spatial frequency and contrast across visual hemifields in left-onset Parkinson's disease: evidence against perceptual hemifield biases.Vision research · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
BACKGROUND/
objectivesVisuospatial problems are common in Parkinson's disease (PD) and likely stem from dysfunction in dopaminergic pathways and consequent disruption of cortical functioning. Characterizing the motor symptoms at disease onset provides a method of observing how dysfunction in these pathways influences visuospatial cognition. We examined two types of motor characteristics: Body side (left or right) and type of initial symptom (tremor or symptom other than tremor).
methods31 non-demented patients with PD, 16 with left-side onset (LPD) and 15 with right-side onset (RPD), as well as 17 healthy control participants (HC). The PD group was also divided by type of initial motor symptom, 15 having tremor as the initial symptom and 16 having an initial symptom other than tremor. Visuospatial function was assessed with the Clock Drawing Test.
resultsOf the four Clock Drawing scoring methods used, the Rouleau method showed sensitivity to subgroup differences. As predicted, the LPD and non-tremor subgroups, but not the other subgroups, performed more poorly than the HC group.
conclusionThe findings provide further evidence for differences in cognition between these subtypes of PD and highlight the importance of considering disease subtypes when examining cognition.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.