ArticlePloS one2014
Risk of childhood overweight after exposure to tobacco smoking in prenatal and early postnatal life.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 5 of them syntheses that pooled it.
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Who cites it
31 citing papers in PubMed, 5 syntheses or guidelines pooled it, 56 citations in OpenAlex.
- Maternal smoking status during pregnancy and low birth weight in offspring: systematic review and meta-analysis of 55 cohort studies published from 1986 to 2020.World journal of pediatrics : WJP · 2022Pooled it
- Pooled it
- Differences in maternal smoking across successive pregnancies - dose-dependent relation to BMI z-score in the offspring: an individual patient data (IPD) meta-analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2018Pooled it
- Maternal smoking during pregnancy and offspring overweight: is there a dose-response relationship? An individual patient data meta-analysis.International journal of obesity (2005) · 2018Pooled it
- Short and long term health effects of parental tobacco smoking during pregnancy and lactation: a descriptive review.Journal of translational medicine · 2015Pooled it
- Caregiver Feeding Practices and Late-Preschool BMI-for-Age z-Score Trajectories Among WIC-Enrolled Children: A National Longitudinal Study.Nutrients · 2026Article
- Maternal Nutritional Environment and the Development of the Melanocortin System.Comprehensive Physiology · 2025Review
- Vaporized nicotine in utero results in reduced birthweight, increased locomotion, and decreased voluntary exercise, dependent on sex and diet in offspring.Psychopharmacology · 2024Article
- Prenatal environmental exposures associated with sex differences in childhood obesity and neurodevelopment.BMC medicine · 2023Article
- Early-life exposure to tobacco and childhood adiposity: Identifying windows of susceptibility.Pediatric obesity · 2022Article
- Prenatal Effects of Nicotine on Obesity Risks: A Narrative Review.International journal of environmental research and public health · 2022Review
- Effect of Exposure to Paternal Smoking on Overweight and Obesity in Children: Findings from the Children Lifeway Cohort in Shenzhen, Southern China.Obesity facts · 2022Article
- Epidemiology of Obesity.Handbook of experimental pharmacology · 2022Article
- Childhood exposure to parental smoking and life-course overweight and central obesity.Annals of medicine · 2021Article
- Phenome-wide investigation of the causal associations between childhood BMI and adult trait outcomes: a two-sample Mendelian randomization study.Genome medicine · 2021Article
- Impact of Carers' Smoking Status on Childhood Obesity in the Growing up in Ireland Cohort Study.International journal of environmental research and public health · 2019Article
- The association between antibiotics in the first year of life and child growth trajectory.BMC pediatrics · 2019Observational
- Multiple imputation methods for handling missing values in a longitudinal categorical variable with restrictions on transitions over time: a simulation study.BMC medical research methodology · 2019Article
- Associations of Prenatal Exposure to Cadmium With Child Growth, Obesity, and Cardiometabolic Traits.American journal of epidemiology · 2019Article
- Maternal Smoking During Pregnancy and Timing of Puberty in Sons and Daughters: A Population-Based Cohort Study.American journal of epidemiology · 2019Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate the association between exposure to mothers smoking during prenatal and early postnatal life and risk of overweight at age 7 years, while taking birth weight into account.
methodsFrom the Danish National Birth Cohort a total of 32,747 families were identified with available information on maternal smoking status in child's pre- and postnatal life and child's birth weight, and weight and height at age 7 years. Outcome was overweight according to the International Obesity Task Force gender and age specific body mass index. Smoking exposure was categorized into four groups: no exposure (n = 25,076); exposure only during pregnancy (n = 3,343); exposure only postnatally (n = 140); and exposure during pregnancy and postnatally (n = 4,188). Risk of overweight according to smoking status as well as dose-response relationships were estimated by crude and adjusted odds ratios using logistic regression models.
resultsExposure to smoking only during pregnancy, or both during pregnancy and postnatally were both significantly associated with overweight at 7 years of age (OR: 1.31, 95% CI: 1.15-1.48, and OR: 1.76, 95% CI: 1.58-1.97, respectively). Analyses excluding children with low birth weight (<2,500 gram) revealed similar results. A significant prenatal dose-response relationship was found. Per one additional cigarette smoked per day an increase in risk of overweight was observed (OR: 1.02, 95% CI: 1.01-1.03). When adjusting for quantity of smoking during pregnancy, prolonged exposure after birth further increased the risk of later overweight in the children (OR 1.28, 95% CI:1.09-1.50) compared with exposure only in the prenatal period.
conclusionsMother's perinatal smoking increased child's OR of overweight at age 7 years irrespective of birth weight, and with higher OR if exposed both during pregnancy and in early postnatal life. Clear dose-response relationships were observed, which emphasizes the need for prevention of any tobacco exposure of infants.
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