Evidence map›Paper›PMID 25310408›Full record

ArticleThe Journal of investigative dermatology2015

Erlotinib-induced skin inflammation is IL-1 mediated in KC-Tie2 mice and human skin organ culture.

Nicole L Ward, Narasimharao Bhagathavula, Andrew Johnston, Sean M Dawes, Wen Fu, Sylviane Lambert, Michael K Dame, Roscoe L Warner, Johann E Gudjonsson, James Varani and 1 more

Open access · greenAbstract readLetter
In one paragraph

Article in The Journal of investigative dermatology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Mouse Models of Psoriasis: A Comprehensive Review.The Journal of investigative dermatology · 2022
    Review
  3. Review
  4. [Establishment of animal models of epidermal growth factor receptor inhibitor-related rashes].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2021
    Article
  5. Review
  6. Review
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Nicole L WardDepartment of Dermatology, Case Western Reserve University, Cleveland, Ohio, USA. Electronic address: jelder@umich.edu.
Narasimharao BhagathavulaDepartment of Pathology, University of Michigan, Ann Arbor, Michigan, USA.
Andrew JohnstonDepartment of Dermatology, University of Michigan, Ann Arbor, Michigan, USA.
Sean M DawesDepartment of Dermatology, Case Western Reserve University, Cleveland, Ohio, USA.
Wen FuDepartment of Dermatology, Case Western Reserve University, Cleveland, Ohio, USA.
Sylviane LambertDepartment of Dermatology, University of Michigan, Ann Arbor, Michigan, USA.
Michael K DameDepartment of Pathology, University of Michigan, Ann Arbor, Michigan, USA.
Roscoe L WarnerDepartment of Pathology, University of Michigan, Ann Arbor, Michigan, USA.
Johann E GudjonssonDepartment of Dermatology, University of Michigan, Ann Arbor, Michigan, USA.
James VaraniDepartment of Pathology, University of Michigan, Ann Arbor, Michigan, USA.
James T ElderDepartment of Dermatology, University of Michigan, Ann Arbor, Michigan, USA; Ann Arbor Veterans Affairs Hospital, Ann Arbor, Michigan, USA. Electronic address: nicole.ward@case.edu.
University of Michigan · USCase Western Reserve University · US

Funding

Vitamin D endocrine system and Protection Against Skin TumorlgenesisP30AR039750 · NIAMS · CASE WESTERN RESERVE UNIVERSITY · PI COOPER, KEVIN D · 1988 to 2015
$9.1M
Systems Biology CoreP50AR055508 · NIAMS · CASE WESTERN RESERVE UNIVERSITY · PI DIAZ-INSUA, MIREYA · 2007 to 2011
$6.8M
IL-17C mediated mechanisms of inflammationR01AR062546 · NIAMS · CASE WESTERN RESERVE UNIVERSITY · PI WARD, NICOLE LEANNE · 2013 to 2017
$1.9M
Remote Inflammation and AtherothrombosisR01AR063437 · NIAMS · CASE WESTERN RESERVE UNIVERSITY · PI WARD, NICOLE LEANNE · 2012 to 2016
$1.7M
Amphiregulin in Psoriatic Epidermal HyperplasiaR01AR052889 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ELDER, JAMES TILFORD · 2006 to 2010
$1.4M
Role of the Psoriasis Associated IL23R Risk Variants on Th17 Biology and FunctionK08AR060802 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GUDJONSSON, JOHANN ELI · 2011 to 2015
$636k
Biologic Activities of IL-36 Cytokines in PsoriasisK01AR064765 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI JOHNSTON, ANDREW · 2013 to 2017
$506k
Neurogenic inflammation and psoriasiform dermatitisR21AR063852 · NIAMS · CASE WESTERN RESERVE UNIVERSITY · PI WARD, NICOLE LEANNE · 2013 to 2014
$370k
NIAMS NIH HHS K01 AR064765NIAMS NIH HHS K08 AR060802NIAMS NIH HHS P30 AR039750NIAMS NIH HHS P30 AR39750NIAMS NIH HHS P50 AR05508NIAMS NIH HHS P50 AR055508NIAMS NIH HHS R01 AR052889NIAMS NIH HHS R01 AR062546NIAMS NIH HHS R01 AR063437NIAMS NIH HHS R21 AR063852
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsBiopsyDermatitisDisease Models, AnimalDose-Response Relationship, DrugErlotinib HydrochlorideHumansHyperplasiaInterleukin-1In Vitro TechniquesMiceMice, TransgenicOrgan Culture TechniquesPhenotypeQuinazolinesReceptor, TIE-2Erlotinib HydrochlorideInterleukin-1QuinazolinesReceptor, TIE-2Tek protein, mouse

Identifiers

PMID25310408
PMCPMC4323891
OpenAlexW2085279736

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.