Evidence map›Paper›PMID 25310000›Full record

ReviewPaediatrics and international child health2014

The stunting syndrome in developing countries.

Andrew J Prendergast, Jean H Humphrey

3 registry-linked trialsOpen access · bronzeAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Paediatrics and international child health, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 430 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
430citing papers in PubMed, 6 pooled it
30.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03801317 nacompletednot on this mapstarted 2018, after this paper: background citation

The Effect of Bovine Colostrum/ Egg Supplementation in Young Malawian Children

TypeinterventionalSponsorWashington University School of MedicineRan2018 to 2020Enrolled278ConditionsStunting, Environmental Enteric DysfunctionArmsBC/ egg, Control, multiple micronutrient
NCT05608928 phase2unknown statusnot on this mapstarted 2022, after this paper: background citation

Ability of the Probiotic Vivomixx to Improve Environmental Enteropathy in Pregnant Women: a Proof of Concept Trial in Bangladesh, Pakistan, Senegal and Zambia

TypeinterventionalSponsorTropical Gastroenterology & Nutrition Group (TROPGAN)Ran2022 to 2023Enrolled76ConditionsEnvironmental EnteropathyArmsVSL#3, Capscan device, Placebo
NCT06676215 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Efficacy of Amino Acid Supplementation on Gut Function and Nutritional Status in FIlipino Children Below Three Years Old

TypeinterventionalSponsorFood and Nutrition Research Institute, PhilippinesRan2025 to 2025Enrolled60ConditionsStunted GrowthArmsIAA mix supplement, Complementary food comprised of rice and legumes
3 · Its place in the literature

Who cites it

430 citing papers in PubMed, 6 syntheses or guidelines pooled it, 1,159 citations in OpenAlex.

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370 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Andrew J Prendergast
Jean H Humphrey
Johns Hopkins University · US

Funding

Wellcome Trust 093768/Z/10/ZWellcome Trust 100714
6 · The paper itself

Abstract

Linear growth failure is the most common form of undernutrition globally. With an estimated 165 million children below 5 years of age affected, stunting has been identified as a major public health priority, and there are ambitious targets to reduce the prevalence of stunting by 40% between 2010 and 2025. We view this condition as a 'stunting syndrome' in which multiple pathological changes marked by linear growth retardation in early life are associated with increased morbidity and mortality, reduced physical, neurodevelopmental and economic capacity and an elevated risk of metabolic disease into adulthood. Stunting is a cyclical process because women who were themselves stunted in childhood tend to have stunted offspring, creating an intergenerational cycle of poverty and reduced human capital that is difficult to break. In this review, the mechanisms underlying linear growth failure at different ages are described, the short-, medium- and long-term consequences of stunting are discussed, and the evidence for windows of opportunity during the life cycle to target interventions at the stunting syndrome are evaluated.

Indexed as

AdolescentAdultChildChild, PreschoolDeveloping CountriesDevelopmental DisabilitiesFemaleGlobal HealthHumansInfantInfant, NewbornMaleMalnutritionPregnancyYoung AdultInfectionsMalnutrition,Mortality,Neurodevelopment,Stunting,

Identifiers

PMID25310000
PMCPMC4232245
OpenAlexW1983214907

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.