Evidence map›Paper›PMID 25309929›Full record

ArticleBioMed research international2014

Serial changes of neointimal tissue after everolimus-eluting stent implantation in porcine coronary artery: an optical coherence tomography analysis.

Hoyoun Won, Jung-Sun Kim, Dong-Ho Shin, Byeong-Keuk Kim, Young-Guk Ko, Donghoon Choi, Yangsoo Jang, Myeong-Ki Hong

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Hoyoun WonChung-Ang University Medical Center, 102 Heukseokro, Dongjak-gu, Seoul 156-755, Republic of Korea.
Jung-Sun KimDivision of Cardiology, Department of Internal Medicine, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Yonsei University Health System, 250 Seongsanno, Seodaemun-go, Seoul 120-752, Republic of Korea ; Cardiovascular Institute, Yonsei University College of Medicine, 250 Seongsanno, Seodaemun-go, Seoul 120-752, Republic of Korea.
Dong-Ho ShinDivision of Cardiology, Department of Internal Medicine, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Yonsei University Health System, 250 Seongsanno, Seodaemun-go, Seoul 120-752, Republic of Korea ; Cardiovascular Institute, Yonsei University College of Medicine, 250 Seongsanno, Seodaemun-go, Seoul 120-752, Republic of Korea.
Byeong-Keuk KimDivision of Cardiology, Department of Internal Medicine, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Yonsei University Health System, 250 Seongsanno, Seodaemun-go, Seoul 120-752, Republic of Korea ; Cardiovascular Institute, Yonsei University College of Medicine, 250 Seongsanno, Seodaemun-go, Seoul 120-752, Republic of Korea.ORCID 0000-0003-2493-066X
Young-Guk KoDivision of Cardiology, Department of Internal Medicine, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Yonsei University Health System, 250 Seongsanno, Seodaemun-go, Seoul 120-752, Republic of Korea ; Cardiovascular Institute, Yonsei University College of Medicine, 250 Seongsanno, Seodaemun-go, Seoul 120-752, Republic of Korea.ORCID 0000-0001-7748-5788
Donghoon ChoiDivision of Cardiology, Department of Internal Medicine, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Yonsei University Health System, 250 Seongsanno, Seodaemun-go, Seoul 120-752, Republic of Korea ; Cardiovascular Institute, Yonsei University College of Medicine, 250 Seongsanno, Seodaemun-go, Seoul 120-752, Republic of Korea.
Yangsoo JangDivision of Cardiology, Department of Internal Medicine, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Yonsei University Health System, 250 Seongsanno, Seodaemun-go, Seoul 120-752, Republic of Korea ; Cardiovascular Institute, Yonsei University College of Medicine, 250 Seongsanno, Seodaemun-go, Seoul 120-752, Republic of Korea ; Severance Biomedical Science Institute, Yonsei University College of Medicine, 250 Seongsanno, Seodaemun-go, Seoul 120-752, Republic of Korea.
Myeong-Ki HongDivision of Cardiology, Department of Internal Medicine, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Yonsei University Health System, 250 Seongsanno, Seodaemun-go, Seoul 120-752, Republic of Korea ; Cardiovascular Institute, Yonsei University College of Medicine, 250 Seongsanno, Seodaemun-go, Seoul 120-752, Republic of Korea ; Severance Biomedical Science Institute, Yonsei University College of Medicine, 250 Seongsanno, Seodaemun-go, Seoul 120-752, Republic of Korea.
Yonsei University · KRChung-Ang University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposesThe serial changes in neointimal tissues were compared between everolimus-eluting stent (EES) and bare-metal stent (BMS) in the porcine coronary artery using optical coherence tomography (OCT).

methodsSerial (1, 3, and 6 month follow-up after stent implantation) OCT examinations were performed in 15 swine with 15 BMS- and 15 EES-treated lesions in porcine coronary arteries.

resultsIn BMS-implanted lesions, neointimal volume decreased from 7.3 mm(3) to 6.9 mm(3) and 6.4 mm(3) at 1, 3, and 6 months follow-up without statistical significance (P = 0.369). At the time points of 1, 3, and 6 months, neointimal tissue appearance was mainly a homogeneous pattern (80.0%, 93.3%, and 100%, resp.), while the other pattern was layered. In contrast, in EES-implanted lesions, neointimal volume significantly increased from 4.8 mm(3) to 9.8 mm(3) between 1 and 3 months but significantly decreased to 8.6 mm(3) between 3 and 6 months (P < 0.001). Between 1 and 3 months, the layered pattern of neointimal tissue increased from 26.7% to 66.7% but decreased to 20.0% between 3 and 6 months.

conclusionsEES had a biphasic pattern of neointimal amounts that correlated with changes in neointimal morphology.

Indexed as

Blood Vessel ProsthesisDrug-Eluting StentsAnimalsCoronary AngiographyCoronary VesselsEverolimusHyperplasiaNeointimaSirolimusSus scrofaTomography, Optical CoherenceEverolimusSirolimus

Identifiers

PMID25309929
PMCPMC4182891
OpenAlexW2007762559

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.