Evidence map›Paper›PMID 25309852›Full record

ArticleGlobal journal of biochemistry2011

Natural antibody - Biochemistry and functions.

Ali Seyar Rahyab, Amit Alam, Aricka Kapoor, Ming Zhang

Open access · greenAbstract read
In one paragraph

Article in Global journal of biochemistry, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact, top 82% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Natural antibodies - facts known and unknown.Central-European journal of immunology · 2018
    Review
  3. A Special Connection between γδ T Cells and Natural Antibodies?Archivum immunologiae et therapiae experimentalis · 2016
    Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ali Seyar RahyabDepartment of Anesthesiology, State University of NewYork Downstate Medical Center, Brooklyn, NY 11203.
Amit AlamDepartment of Anesthesiology, State University of NewYork Downstate Medical Center, Brooklyn, NY 11203.
Aricka KapoorCUNY Brooklyn College, Brooklyn, NY 11210.
Ming ZhangDepartment of Anesthesiology, State University of NewYork Downstate Medical Center, Brooklyn, NY 11203 ; Department of Cell Biology, State University of NewYork Downstate Medical Center, Brooklyn, NY 11203.
Brooklyn College · US

Funding

The role of autoimmune natural IgM in human myocardial infarctionR21HL088527 · NHLBI · SUNY DOWNSTATE MEDICAL CENTER · PI ZHANG, MING · 2009 to 2010
$425k
NHLBI NIH HHS R21 HL088527
6 · The paper itself

Abstract

Natural antibodies have been common knowledge in the scientific community for more than half a century. Initially disregarded, their functions have garnered a newfound interest recently. Natural antibodies are usually polyreactive IgM antibodies and are implicated in numerous physiologic and pathologic processes. Current research demonstrates they play a role in adaptive and innate immune responses, autoimmunity, and apoptosis. Evidence exists that they are involved in the modulation of neurodegenerative disorders and malignancy. Furthermore, natural antibodies have been implicated in ischemia reperfusion injury and atherosclerosis. As such the study of natural antibodies may provide new insight into normal physiologic processes whilst concurrently paving the road for a wide-range of possible therapeutic options.

Indexed as

ComplementFunctionNatural antibodyPathobiologyPhysiologyStructure

Identifiers

PMID25309852
PMCPMC4189112
OpenAlexW2248211661

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.