Evidence map›Paper›PMID 25309711›Full record

ReviewNeurology international2014

Another Perspective on Fasciculations: When is it not Caused by the Classic form of Amyotrophic Lateral Sclerosis or Progressive Spinal Atrophy?

Marco Antonio Araujo Leite, Marco Orsini, Marcos R G de Freitas, João Santos Pereira, Fábio Henrique Porto Gobbi, Victor Hugo Bastos, Dionis de Castro Machado, Sergio Machado, Oscar Arrias-Carrion, Jano Alves de Souza and 1 more

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Neurology international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05718011 (Comparison of Prophylactic Use of Dexmedetomidine and Ketamine for Prevention of Shivering After Spinal Anesthesia), which is not on this map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05718011 phase4completednot on this mapstarted 2021, after this paper: background citation

Comparison of Prophylactic Use of Dexmedetomidine and Ketamine for Prevention of Shivering After Spinal Anesthesia

TypeinterventionalSponsorPakistan Air Force (PAF) Hospital IslamabadRan2021 to 2021Enrolled116ConditionsPostoperative ShiveringArmsDexmedetomidine, Ketamine
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Marco Antonio Araujo LeiteNeurology Service, Movement Disorders Unit, Fluminense Federal University , Niterói, Rio de Janeiro, Brazil.
Marco OrsiniNeurology Service, Movement Disorders Unit, Fluminense Federal University , Niterói, Rio de Janeiro, Brazil.
Marcos R G de FreitasNeurology Service, Movement Disorders Unit, Fluminense Federal University , Niterói, Rio de Janeiro, Brazil.
João Santos PereiraNeurology Service, Movement Disorders Unit, Fluminense Federal University , Niterói, Rio de Janeiro, Brazil ; Neurology Service, Rio de Janeiro University , Brazil.
Fábio Henrique Porto GobbiNeurology Department, São Paulo University , Brazil.
Victor Hugo BastosDepartament of Physiotherapy, Piaui Federal University , Parnaíba, Brazil.
Dionis de Castro MachadoDepartament of Physiotherapy, Piaui Federal University , Parnaíba, Brazil.
Sergio MachadoPhysical Activity Neuroscience, Physical Activity Sciences Postgraduate Program, Salgado de Oliveira University , Niterói, Brazil.
Oscar Arrias-CarrionMovement Disorders and Sleep Unit, General Hospital Dr. Manuel Gea González, Secretaria de México D.F. , México.
Jano Alves de SouzaNeurology Service, Movement Disorders Unit, Fluminense Federal University , Niterói, Rio de Janeiro, Brazil.
Acary Bulle OliveiraNeurology Service, São Paulo Federal University , São Paulo, Brazil.
Universidade Federal Fluminense · BRUniversidade Federal do Piauí · BRUniversidade Federal de São Paulo · BRUniversidade Salgado de Oliveira · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fasciculations are visible, fine and fast, sometimes vermicular contractions of fine muscle fibers that occur spontaneously and intermittently. The aim of this article is to discuss the main causes for fasciculations and their pathophysiology in different sites of the central/peripheral injury and in particular to disprove that the presence of this finding in the neurological examination is indicative of amyotrophic lateral sclerosis. Undoubtedly, most fasciculations have a distal origin in the motor nerve both in normal subjects and in patients with motor neuron disease. Most of them spread to other dendritic spines often producing an antidromic impulse in the main axon. The clinical and neurophysiological diagnosis must be thorough. It may often take long to record fasciculations with electroneuromyography. In other cases, temporal monitoring is necessary before the diagnosis. The treatment, which may be adequate in some cases, is not always necessary.

Indexed as

electromyography treatmentfasciculationsneurological diseases

Identifiers

PMID25309711
PMCPMC4192433
OpenAlexW2155394463

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.