Evidence map›Paper›PMID 25309504›Full record

ReviewFrontiers in neurology2014

Management of fatigue in persons with multiple sclerosis.

Fary Khan, Bhasker Amatya, Mary Galea

Registry-linked trialAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in neurology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06051019 (Comparison Between the Effects on Fatigue of Aerobic Training Versus Balance Training in Patients With Multiple Sclerosis), which is not on this map. Cited by 58 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06051019 nacompletednot on this mapstarted 2016, after this paper: background citation

Comparison Between the Effects on Fatigue of Aerobic Training Versus Balance Training in Patients With Multiple Sclerosis: a Randomised Crossover Trial.

TypeinterventionalSponsorIstituto Auxologico ItalianoRan2016 to 2019Enrolled39ConditionsMultiple SclerosisArmsAerobic training, Balance training
3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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  7. Comparing two relaxation procedures to ease fatigue in multiple sclerosis: a single-blind randomized controlled trial.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Fary KhanDepartment of Rehabilitation Medicine, Royal Melbourne Hospital , Melbourne, VIC , Australia ; The University of Melbourne , Melbourne, VIC , Australia ; School of Public Health and Preventive Medicine, Monash University , Melbourne, VIC , Australia.
Bhasker AmatyaDepartment of Rehabilitation Medicine, Royal Melbourne Hospital , Melbourne, VIC , Australia.
Mary GaleaDepartment of Rehabilitation Medicine, Royal Melbourne Hospital , Melbourne, VIC , Australia ; The University of Melbourne , Melbourne, VIC , Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fatigue is one of the most common symptoms of multiple sclerosis. Despite advances in pharmacological and non-pharmacological treatment, fatigue continues to be the disabling symptom in persons with MS (pwMS), affecting almost 80% of pwMS. In current practice, both pharmacological and non-pharmacological interventions are used in combination, encompassing a multi-disciplinary approach. The body of research investigating the effect of these interventions is growing. This review systematically evaluated the existing evidence on the effectiveness and safety of different interventions currently applied for the management of fatigue in person with multiple sclerosis in improving patient outcomes, to guide treating clinicians.

Indexed as

disabilityfatiguemultiple sclerosisrehabilitation outcomessymptomatic treatment

Identifiers

PMID25309504
PMCPMC4163985

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.