ArticleFrontiers in integrative neuroscience2014
Origins of strabismus and loss of binocular vision.
Article in Frontiers in integrative neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07563959 (Efficacy of Visual Therapy in Intermittent Non-Pathological Horizontal Strabismus), which is not on this map. Cited by 44 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Efficacy of Visual Therapy in Intermittent Non-Pathological Horizontal Strabismus: A Randomized Controlled Trial
Who cites it
44 citing papers in PubMed, 90 citations in OpenAlex.
- Evaluation of retinal microvasculature in exotropia with abnormal binocular vision by optical coherence tomography angiography.BMC ophthalmology · 2023Trial
- Understanding clinical features, predictors of late presentation, and caregiver perspectives and awareness of strabismus in children: a cross-sectional study in a sub-Saharan African setting.BMC ophthalmology · 2026Article
- Review
- Mean Apparent Propagator MRI: A Potential Imaging Biomarker of Brain Microstructural Alterations in Basic-Type Intermittent Exotropia.Investigative ophthalmology & visual science · 2026Article
- Device closure of a small atrial septal defect with an unusual set of post-operative complications.BMC cardiovascular disorders · 2026Article
- Visual acuity problems, access to care, and related academic performance among primary school students in Tanzania: a mixed methods study.Vulnerable children and youth studies · 2026Article
- Cortex-Restricted Deletion of Foxp1 Impairs Visual Responses by Disrupting Geniculocortical Connections in a Mouse Model of Autism.Investigative ophthalmology & visual science · 2026Article
- A bibliometric analysis of publication trends in strabismus over the past 30y.International journal of ophthalmology · 2026Article
- Orthoptic Treatment After Strabismus Surgery in Child Intermittent Divergent Strabismus.Children (Basel, Switzerland) · 2026Article
- Article
- Comparison of orbital structures between age-related distance esotropia and acute acquired concomitant esotropia.PloS one · 2025Article
- A Bibliometric Analysis of Strabismus Research Literature : Strabismus Research Trends.Galen medical journal · 2025Review
- Pilot Study Comparing the Ocular Deviation Measures of Basic Intermittent Exotropia Using 2WIN-S and Prism Cover Test.The British and Irish orthoptic journal · 2025Article
- Altered static and dynamic functional connectivity in childhood basic-type intermittent exotropia.Brain communications · 2025Article
- Making stereopsis related to the ability of ocular deviation: a new paradigm for assessment of intermittent exotropia.International journal of ophthalmology · 2025Article
- Maternal Hypertensive Disorder in Pregnancy and Childhood Strabismus in Offspring.JAMA network open · 2024Article
- Abnormal occipital and frontal activity during voluntary convergence in intermittent exotropia: A task-fMRI study.Heliyon · 2024Article
- A protocol to quantify cross-sectional and longitudinal differences in duction patterns.Frontiers in neuroscience · 2024Article
- EEG measurement for the effect of perceptual eye position and eye position training on comitant strabismus.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Comitant strabismus etiology: extraocular muscle integrity and central nervous system involvement-a narrative review.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Strabismus is a frequent ocular disorder that develops early in life in humans. As a general rule, it is characterized by a misalignment of the visual axes which most often appears during the critical period of visual development. However other characteristics of strabismus may vary greatly among subjects, for example, being convergent or divergent, horizontal or vertical, with variable angles of deviation. Binocular vision may also vary greatly. Our main goal here is to develop the idea that such "polymorphy" reflects a wide variety in the possible origins of strabismus. We propose that strabismus must be considered as possibly resulting from abnormal genetic and/or acquired factors, anatomical and/or functional abnormalities, in the sensory and/or the motor systems, both peripherally and/or in the brain itself. We shall particularly develop the possible "central" origins of strabismus. Indeed, we are convinced that it is time now to open this "black box" in order to move forward. All of this will be developed on the basis of both presently available data in literature (including most recent data) and our own experience. Both data in biology and medicine will be referred to. Our conclusions will hopefully help ophthalmologists to better understand strabismus and to develop new therapeutic strategies in the future. Presently, physicians eliminate or limit the negative effects of such pathology both on the development of the visual system and visual perception through the use of optical correction and, in some cases, extraocular muscle surgery. To better circumscribe the problem of the origins of strabismus, including at a cerebral level, may improve its management, in particular with respect to binocular vision, through innovating tools by treating the pathology at the source.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.