ArticleFrontiers in neuroanatomy2014
Unimodal primary sensory cortices are directly connected by long-range horizontal projections in the rat sensory cortex.
Article in Frontiers in neuroanatomy, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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44 citing papers in PubMed.
- Excitatory and inhibitory networks diverge following early blindness.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Seeing what you hear: Compression of rat visual perceptual space by task-irrelevant sounds.PLoS computational biology · 2025Article
- Auditory cortex learns to discriminate audiovisual cues through selective multisensory enhancement.eLife · 2025Article
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- Stability of cross-sensory input to primary somatosensory cortex across experience.bioRxiv : the preprint server for biology · 2024Article
- A primary sensory cortical interareal feedforward inhibitory circuit for tacto-visual integration.Nature communications · 2024Article
- Separation of bimodal fMRI responses in mouse somatosensory areas into V1 and non-V1 contributions.Scientific reports · 2024Article
- Unpacking the navigation toolbox: insights from comparative cognition.Proceedings. Biological sciences · 2024Review
- The Development of Multisensory Integration at the Neuronal Level.Advances in experimental medicine and biology · 2024Article
- Integrating Visual Information into the Auditory Cortex Promotes Sound Discrimination through Choice-Related Multisensory Integration.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Stimulus Feature-Specific Control of Layer 2/3 Subthreshold Whisker Responses by Layer 4 in the Mouse Primary Somatosensory Cortex.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- Sensory stimulation-based protection from impending stroke following MCA occlusion is correlated with desynchronization of widespread spontaneous local field potentials.Scientific reports · 2022Article
- Hearing, touching, and multisensory integration during mate choice.Frontiers in neural circuits · 2022Review
- Visual modulation of firing and spectrotemporal receptive fields in mouse auditory cortex.Current research in neurobiology · 2022Article
- Neocortical Layer 1: An Elegant Solution to Top-Down and Bottom-Up Integration.Annual review of neuroscience · 2021Article
- Subcortical circuits mediate communication between primary sensory cortical areas in mice.Nature communications · 2021Article
- Axonal and Dendritic Morphology of Excitatory Neurons in Layer 2/3 Mouse Barrel Cortex Imaged Through Whole-Brain Two-Photon Tomography and Registered to a Digital Brain Atlas.Frontiers in neuroanatomy · 2021Article
- Cortical Hub for Flavor Sensation in Rodents.Frontiers in systems neuroscience · 2021Review
- Approaches to Understanding Multisensory Dysfunction in Autism Spectrum Disorder.Autism research : official journal of the International Society for Autism Research · 2020Review
- Unisensory and Multisensory Responses in Fetal Alcohol Spectrum Disorders (FASD): Effects of Spatial Congruence.Neuroscience · 2020Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Research based on functional imaging and neuronal recordings in the barrel cortex subdivision of primary somatosensory cortex (SI) of the adult rat has revealed novel aspects of structure-function relationships in this cortex. Specifically, it has demonstrated that single whisker stimulation evokes subthreshold neuronal activity that spreads symmetrically within gray matter from the appropriate barrel area, crosses cytoarchitectural borders of SI and reaches deeply into other unimodal primary cortices such as primary auditory (AI) and primary visual (VI). It was further demonstrated that this spread is supported by a spatially matching underlying diffuse network of border-crossing, long-range projections that could also reach deeply into AI and VI. Here we seek to determine whether such a network of border-crossing, long-range projections is unique to barrel cortex or characterizes also other primary, unimodal sensory cortices and therefore could directly connect them. Using anterograde (BDA) and retrograde (CTb) tract-tracing techniques, we demonstrate that such diffuse horizontal networks directly and mutually connect VI, AI and SI. These findings suggest that diffuse, border-crossing axonal projections connecting directly primary cortices are an important organizational motif common to all major primary sensory cortices in the rat. Potential implications of these findings for topics including cortical structure-function relationships, multisensory integration, functional imaging, and cortical parcellation are discussed.
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