Evidence map›Paper›PMID 25309081›Full record

SynthesisWorld journal of gastroenterology2014

Review of experimental attempts of islet allotransplantation in rodents: parameters involved and viability of the procedure.

Leandro Ryuchi Iuamoto, Alberto Meyer, Eleazar Chaib, Luiz Augusto Carneiro D'Albuquerque

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in World journal of gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Leandro Ryuchi IuamotoLeandro Ryuchi Iuamoto, Alberto Meyer, Eleazar Chaib, Luiz Augusto Carneiro D'Albuquerque, Department of Gastroenterology, Liver and Pancreas Transplantation Surgery Unit, University of Sao Paulo, Sao Paulo 05403-090, Brazil.
Alberto MeyerLeandro Ryuchi Iuamoto, Alberto Meyer, Eleazar Chaib, Luiz Augusto Carneiro D'Albuquerque, Department of Gastroenterology, Liver and Pancreas Transplantation Surgery Unit, University of Sao Paulo, Sao Paulo 05403-090, Brazil.
Eleazar ChaibLeandro Ryuchi Iuamoto, Alberto Meyer, Eleazar Chaib, Luiz Augusto Carneiro D'Albuquerque, Department of Gastroenterology, Liver and Pancreas Transplantation Surgery Unit, University of Sao Paulo, Sao Paulo 05403-090, Brazil.
Luiz Augusto Carneiro D'AlbuquerqueLeandro Ryuchi Iuamoto, Alberto Meyer, Eleazar Chaib, Luiz Augusto Carneiro D'Albuquerque, Department of Gastroenterology, Liver and Pancreas Transplantation Surgery Unit, University of Sao Paulo, Sao Paulo 05403-090, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of the present study was to organize the parameters involved in experimental allotransplantation in rodents to elaborate the most suitable model to supply the scarcity of islet donors. We used the PubMed database to systematically search for published articles containing the keywords "rodent islet transplantation" to review. We included studies that involved allotransplantation experiments with rodents' islets, and we reviewed the reference lists from the eligible publications that were retrieved. We excluded articles related to isotransplantation, autotransplantation and xenotransplantation, i.e., transplantation in other species. A total of 25 studies related to allotransplantation were selected for systematic review based on their relevance and updated data. Allotransplantation in rodents is promising and continues to develop. Survival rates of allografts have increased with the discovery of new immunosuppressive drugs and the use of different graft sites. These successes suggest that islet transplantation is a promising method to overcome the scarcity of islet donors and advance the treatment options for type 1 diabetes.

Indexed as

Graft SurvivalIslets of Langerhans TransplantationAllograftsAnimalsDiabetes Mellitus, Type 1Graft RejectionImmunosuppressive AgentsIslets of LangerhansMiceRatsTissue SurvivalImmunosuppressive AgentsAllograftDiabetes mellitusHyperglycemiaImmunosuppressionIsletIslet graftsIslet transplantationType 1 diabetes

Identifiers

PMID25309081
PMCPMC4188902

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.