Evidence map›Paper›PMID 25309060›Full record

ReviewWorld journal of gastroenterology2014

Biological therapy for ulcerative colitis: an update.

Geom Seog Seo, Soo-Cheon Chae

Abstract readReview
In one paragraph

Review in World journal of gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
  2. Article
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Article
  8. Oncotarget · 2017
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
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  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Geom Seog SeoGeom Seog Seo, Department of Gastroenterology, Wonkwang University School of Medicine, Digestive Disease Research Institute, Chonbuk 570-749, South Korea.
Soo-Cheon ChaeGeom Seog Seo, Department of Gastroenterology, Wonkwang University School of Medicine, Digestive Disease Research Institute, Chonbuk 570-749, South Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Of the diverse biological agents used for patients with ulcerative colitis, the anti-tumor necrosis factor-α agents infliximab and adalimumab have been used in large-scale clinical trials and are currently widely used in the treatment of inflammatory bowel disease patients. Recent studies have indicated that golimumab, oral tofacitinib and vedolizumab reportedly achieved good clinical response and remission rates in ulcerative colitis patients. Thus, we believe that the detailed investigation of various studies on clinical trials may provide important information for the selection of appropriate biological agents, and therefore, we have extensively reviewed such trials in the present study.

Indexed as

Biological ProductsColitis, UlcerativeGastrointestinal AgentsHumansMolecular Targeted TherapyRemission InductionSignal TransductionTreatment OutcomeTumor Necrosis Factor-alphaBiological ProductsGastrointestinal AgentsTumor Necrosis Factor-alphaBiological therapyClinical trialImmune dysfunctionInflammatory bowel diseaseRemissionUlcerative colitis

Identifiers

PMID25309060
PMCPMC4188881

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.