ReviewWorld journal of gastroenterology2014
Treatment of peri-anal fistula in Crohn's disease.
Review in World journal of gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Dose-dependent efficacy and safety of Filgotinib in moderate to severe Crohn's disease: a grade-assessed systematic review and meta-analysis of randomized controlled trials.European journal of clinical pharmacology · 2025Pooled it
- Efficacy and Safety of Filgotinib for the Treatment of Perianal Fistulising Crohn's Disease [DIVERGENCE 2]: A Phase 2, Randomised, Placebo-controlled Trial.Journal of Crohn's & colitis · 2024Trial
- Darvadstrocel for Complex Perianal Fistulas in Japanese Adults with Crohn's Disease: A Phase 3 Study.Journal of Crohn's & colitis · 2023Trial
- Sequence-robust MRI asymmetry measures for the detection of anoperineal lesions in Crohn's disease on axial pelvic MRI scans.PloS one · 2026Article
- Prognostic Value of Serum Insulin-Like Growth Factor-1 in Patients With Anal Fistula Treated by Incision-Thread-Drawing Surgery.Annals of gastroenterological surgery · 2025Article
- Prolonged Time to Diagnosis of Crohn's Disease in Patients With Perianal Fistulas Negatively Affects Long-Term Outcomes.Journal of Crohn's & colitis · 2025Article
- Perianal fistulizing lesions of Crohn's disease are associated with long-term behavior and its transition: a Chinese cohort study.Intestinal research · 2024Article
- Article
- Crohn's Disease-Associated and Cryptoglandular Fistulas: Differences and Similarities.Journal of clinical medicine · 2023Review
- Autologous Bioactive Compound Concentrated Growth Factor Ameliorates Fistula Healing of Anal Fistula in a Pig Model and Promotes Proliferation and Migration of Human Skin Fibroblasts via Regulating the MEK/ERK Pathway.Oxidative medicine and cellular longevity · 2022Article
- Journey through Crohn's Disease Complication: From Fistula Formation to Future Therapies.Journal of clinical medicine · 2021Review
- Outcomes of Pediatric Fistulising Perianal Crohn's Disease.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2021Article
- Ambulatory management of perianal Crohn's disease during the COVID-19 pandemic.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2020Article
- The Role of Inflammation in Crohn's Disease Recurrence after Surgical Treatment.Journal of immunology research · 2020Review
- The Role of Active Inflammation and Surgical Therapy in Crohn's Disease Recurrence.Gastroenterology research and practice · 2020Review
- Permacol™ collagen paste for cryptoglandular and Crohn's anal fistula.Techniques in coloproctology · 2019Article
- Perianal Fistulas in Patients With Crohn's Disease, Part 2: Surgical, Endoscopic, and Future Therapies.Gastroenterology & hepatology · 2018Article
- Perianal Fistulas in Patients With Crohn's Disease, Part 1: Current Medical Management.Gastroenterology & hepatology · 2018Article
- Ambulatory Surgery for Perianal Crohn's Disease: Study of Feasibility.Gastroenterology research and practice · 2018Article
- Advances in endoscopic ultrasound imaging of colorectal diseases.World journal of gastroenterology · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Anal fistulas are a common manifestation of Crohn's disease (CD). The first manifestation of the disease is often in the peri-anal region, which can occur years before a diagnosis, particularly in CD affecting the colon and rectum. The treatment of peri-anal fistulas is difficult and always multidisciplinary. The European guidelines recommend combined surgical and medical treatment with biologic drugs to achieve best results. Several different surgical techniques are currently employed. However, at the moment, none of these techniques appear superior to the others in terms of healing rate. Surgery is always indicated to treat symptomatic, simple, low intersphincteric fistulas refractory to medical therapy and those causing disabling symptoms. Utmost attention should be paid to correcting the balance between eradication of the fistula and the preservation of fecal continence.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.