Evidence map›Paper›PMID 25308768›Full record

ArticleHeart & lung : the journal of critical care

COPD is associated with cognitive dysfunction and poor physical fitness in heart failure.

Michael L Alosco, Mary Beth Spitznagel, Richard Josephson, Joel Hughes, John Gunstad

Abstract read
In one paragraph

Article in Heart & lung : the journal of critical care. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Cognition and Exercise: GENERAL OVERVIEW AND IMPLICATIONS FOR CARDIAC REHABILITATION.Journal of cardiopulmonary rehabilitation and prevention · 2021
    Article
  5. Article
  6. Article
  7. Reduced Attention in Former Smokers with and without COPD.International journal of behavioral medicine · 2019
    Article
  8. Cognitive decline in heart failure.Heart failure reviews · 2016
    Review
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Michael L AloscoDepartment of Psychological Sciences, Kent State University, Kent, OH 44242, USA.
Mary Beth SpitznagelDepartment of Psychological Sciences, Kent State University, Kent, OH 44242, USA; Department of Psychiatry, Summa Health System, Akron City Hospital, Akron, OH, USA.
Richard JosephsonDepartment of Medicine, University Hospitals Case Medical Center, Cleveland, USA; Harrington Heart & Vascular Institute, Cleveland, OH, USA; Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Joel HughesDepartment of Psychological Sciences, Kent State University, Kent, OH 44242, USA; Department of Psychiatry, Summa Health System, Akron City Hospital, Akron, OH, USA.
John GunstadDepartment of Psychological Sciences, Kent State University, Kent, OH 44242, USA. Electronic address: jgunstad@kent.edu.

Funding

Cognitive Benefits of Cardiac Rehabilitation in Heart FailureR01HL089311 · NHLBI · KENT STATE UNIVERSITY · PI GUNSTAD, JOHN J. · 2008 to 2012
$2.6M
Cognitive Effects of Bariatric SurgeryR01DK075119 · NIDDK · KENT STATE UNIVERSITY · PI GUNSTAD, JOHN J. · 2006 to 2009
$1.5M
Extended Effects of Bariatric Surgery on Cognitive FunctionR56DK075119 · NIDDK · KENT STATE UNIVERSITY · PI GUNSTAD, JOHN J. · 2010 to 2010
$296k
NHLBI NIH HHS HL089311NHLBI NIH HHS R01 HL089311NIDDK NIH HHS DK075119NIDDK NIH HHS R01 DK075119NIDDK NIH HHS R56 DK075119
6 · The paper itself

Abstract

objectiveTo examine the associations among chronic obstructive pulmonary disease (COPD), cognitive function, and physical fitness in heart failure (HF).

backgroundCognitive impairment in HF in part stems from medical comorbidities and poor physical fitness. COPD, a frequent co-existing condition in HF, is a risk factor for cognitive impairment and a known cause of poor physical fitness. Yet, the interplay among COPD, cognition, and physical fitness has never been examined in HF.

methods191 HF patients completed a cognitive test battery and brief physical fitness assessment. Diagnostic history of COPD was ascertained via medical chart review.

resultsRegression analyses showed HF patients with COPD exhibited worse attention/executive function and poorer fitness relative to their non-COPD counterparts. Worse fitness correlated with cognitive dysfunction.

conclusionsCOPD is associated with reduced cognition and worse fitness in HF. Longitudinal work that employs objective assessments of COPD is needed to determine directionality and clarify mechanisms.

Indexed as

AgedAttentionCognitionCognition DisordersCross-Sectional StudiesExecutive FunctionFemaleHeart FailureHumansMaleMiddle AgedNeuropsychological TestsPhysical FitnessPulmonary Disease, Chronic ObstructiveRegression AnalysisRisk FactorsCognitive functionCOPDHeart failurePhysical fitness

Identifiers

PMID25308768
PMCPMC4267965

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.