ArticleBMC pediatrics2014
Chronic pain treatment in children and adolescents: less is good, more is sometimes better.
Article in BMC pediatrics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03686748 (Retuning the Nervous System in Youth With Chronic Pain), which is not on this map. Cited by 20 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Retuning the Nervous System in Youth With Chronic Pain
Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 80 citations in OpenAlex.
- [Pediatric inpatient interdisciplinary multimodal pain treatment in Germany].Schmerz (Berlin, Germany) · 2024Pooled it
- Pooled it
- Systematic Review on Intensive Interdisciplinary Pain Treatment of Children With Chronic Pain.Pediatrics · 2015Pooled it
- The effect of a smartphone-based pain management application on pain intensity and quality of life in adolescents with chronic pain.Scientific reports · 2021Trial
- Pain-related fear in adolescents with chronic musculoskeletal pain: process evaluation of an interdisciplinary graded exposure program.BMC health services research · 2020Trial
- Brain-immune correlates of quality of life in adolescents with chronic musculoskeletal pain.Brain, behavior, and immunity · 2026Article
- Attrition from Face-to-Face Pediatric Outpatient Chronic Pain Interventions: A Narrative Review and Theoretical Model.Children (Basel, Switzerland) · 2024Review
- Influencing factors of chronic pain after total knee replacement in osteoarthritis patients: a nomogram prediction model.American journal of translational research · 2024Article
- [Medical pain care for children and adolescents with chronic pain in Germany : An inventory].Schmerz (Berlin, Germany) · 2021Article
- Self-reported specific learning disorders and risk factors among Hungarian adolescents with functional abdominal pain disorders: a cross sectional study.BMC pediatrics · 2020Article
- End points for sickle cell disease clinical trials: patient-reported outcomes, pain, and the brain.Blood advances · 2019Article
- Children With Chronic Pain: Response Trajectories After Intensive Pain Rehabilitation Treatment.The journal of pain · 2018Article
- Somatic symptom and related disorders in children and adolescents: evaluation of a naturalistic inpatient multidisciplinary treatment.Child and adolescent psychiatry and mental health · 2018Article
- [Therapy outcome one year after pediatric outpatient chronic pain evaluation : Chronic Pain Grading (CPG) for adolescent pain patients].Schmerz (Berlin, Germany) · 2017Article
- [Definition, diagnostics and therapy of chronic widespread pain and the (so-called) fibromyalgia syndrome in children and adolescents : Updated guidelines 2017].Schmerz (Berlin, Germany) · 2017Review
- Chronic Pain in Children: A Look at the Referral Process to a Pediatric Pain Clinic.International journal of pediatrics · 2017Article
- Specialized Rehabilitation Programs for Children and Adolescents with Severe Disabling Chronic Pain: Indications, Treatment and Outcomes.Children (Basel, Switzerland) · 2016Review
- [Therapy recommendations in a pediatric outpatient pain clinic : Adherence and effectiveness of implementation].Schmerz (Berlin, Germany) · 2016Article
- Subanesthetic ketamine infusions for the treatment of children and adolescents with chronic pain: a longitudinal study.BMC pediatrics · 2015Article
- Pain stickiness in pediatric complex regional pain syndrome: A role for the nucleus accumbens.Neurobiology of pain (Cambridge, Mass.)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn children with chronic pain, interdisciplinary outpatient and intensive inpatient treatment has been shown to improve pain intensity and disability. However, there are few systematic comparisons of outcomes of the two treatments. The present naturalistic study aimed to compare the clinical presentation and achieved changes at return in three outcome domains (pain intensity, disability, school absence) between a) outpatients vs. inpatients and b) patients who declined intensive inpatient treatment and completed outpatient treatment instead (decliners) vs. those who completed inpatient treatment (completers).
methodsThe study compared treatment outcomes between n = 992 outpatients vs. n = 320 inpatients (Analysis A) who were treated at a tertiary treatment centre and returned for a return visit within a one-year interval. In Analysis B, treatment outcomes were compared between n = 67 decliners vs. n = 309 completers of inpatient treatment. The three outcome domains were compared by calculating standardized change scores and clinically significant changes.
resultsIn analysis A, outpatients and inpatients reported comparably low levels of pain intensity (NRS 0-10; mean = 4, SD = 2.7) and disability (Paediatric Pain Disability Index (PPDI: 12-60; mean = 24; SD = 10) at the return visit. Compared to outpatients, more inpatients achieved clinically significant changes in pain intensity (52% vs. 45%) and disability (46% vs. 31%). There were also significantly greater changes in disability in the inpatient group (change score outpatients = 1.0; change score inpatients = 1.4; F(1,1138) = 12.6, p = .011). School absence was substantially reduced, with approximately 80% in each group attending school regularly. Analysis B showed that even though inpatient decliners achieved improvements in the outcome domains, they reported greater disability at the return visit (PPDI mean decliners = 27, SD = 9.9; PPDI mean completers = 24, SD = 10) because they had achieved fewer changes in disability (change score decliners = 0.9; change score completers = 1.4; F(1.334) = 5.7, p = .017). In addition, less decliners than completers achieved clinically significant changes in disability (25% vs. 47%).
conclusionsInpatient and outpatient treatments are able to elicit substantial changes in pain intensity, disability and school absence. The results highlight the necessity of intensive inpatient pain treatment for highly affected children, as children who declined inpatient treatment and were treated as outpatients did less well.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.