Evidence map›Paper›PMID 25308385›Full record

ReviewCurrent psychiatry reports2014

Neuroimaging and biomarkers in addiction treatment.

Kathleen A Garrison, Marc N Potenza

Registry-linked trialAbstract readReview
In one paragraph

Review in Current psychiatry reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06073340 (Observational Longitudinal Study of Individuals With Stimulant Use Disorder), which is not on this map. Cited by 41 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 3 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06073340 terminatednot on this mapstarted 2023, after this paper: background citation

Observational Longitudinal Study of Individuals With Stimulant Use Disorder: Research and Development of a Biosignature

TypeobservationalSponsorUniversity of Texas Southwestern Medical CenterRan2023 to 2025Enrolled72ConditionsStimulant Use, Stimulant-Related Disorder, Healthy
3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 3 syntheses or guidelines pooled it, 74 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Modified cognitive behavioral therapy (M-CBT) for cocaine dependence: Development of treatment for cognitively impaired users and results from a Stage 1 trial.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2018
    Trial
  6. Article
  7. Article
  8. Review
  9. Review
  10. Neuroimaging Biomarkers in Addiction.medRxiv : the preprint server for health sciences · 2024
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Kathleen A GarrisonDepartment of Psychiatry, Yale University School of Medicine, 1 Church Street, Room 730, New Haven, CT, 06510, USA, kathleen.garrison@yale.edu.
Marc N Potenza
Yale University · US

Funding

TSF to enhance treatment of cocaine dependenceP50DA009241 · NIDA · YALE UNIVERSITY · PI CARROLL, KATHLEEN M. · 1994 to 2018
$40.5M
SUBSTANCE ABUSEK12DA000167 · NIDA · YALE UNIVERSITY · PI STEPHANIE S O'MALLEY, Marc N Potenza · 1991 to 2026
$17.7M
Translational Research of Cocaine, Striatum, and ImpulsivitiesP20DA027844 · NIDA · YALE UNIVERSITY · PI POTENZA, MARC N · 2010 to 2013
$3.6M
Neural mechanisms of CBT in cocaine dependence (Gender Differences Supplement)R01DA035058 · NIDA · YALE UNIVERSITY · PI CARROLL, KATHLEEN M., POTENZA, MARC N · 2013 to 2016
$2.3M
NIDA NIH HHS K12 DA000167NIDA NIH HHS P20 DA027844NIDA NIH HHS P50 DA009241NIDA NIH HHS P50 DA09241NIDA NIH HHS R01 DA035058
6 · The paper itself

Abstract

Neuroimaging studies have made a significant contribution to the efforts to identify measurable indices, or biomarkers, of addictions and their treatments. Biomarkers in addiction treatment are needed to provide targets for treatment, detect treatment subgroups, predict treatment response, and broadly improve outcomes. Neuroimaging is important to biomarkers research as it relates neural circuits to both molecular mechanisms and behavior. A focus of recent efforts in neuroimaging in addiction has been to elucidate the neural correlates associated with dimensions of functioning in substance-use and related disorders, such as cue-reactivity, impulsivity, and cognitive control, among others. These dimensions of functioning have been related to addiction treatment outcomes and relapse, and therefore, a better understanding of these dimensions and their neural correlates may help to identify brain-behavior biomarkers of treatment response. This paper reviews recent neuroimaging studies that report potential biomarkers in addiction treatment related to cue-reactivity, impulsivity, and cognitive control, as well as recent advances in neuroimaging that may facilitate efforts to determine reliable biomarkers. This important initial work has begun to identify possible mediators and moderators of treatment response, and multiple promising indices are being tested.

Indexed as

BiomarkersExecutive FunctionHumansImpulsive BehaviorNeuroimagingSubstance-Related DisordersBiomarkers

Identifiers

PMID25308385
PMCPMC4427893
OpenAlexW2076126682

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.